Results 111 to 120 of about 11,303,965 (300)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The Canonical Extensive Form of a Game Form - Part II - Representation [PDF]
This paper exhibits to any noncooperative game in strategic or normal form a 'canonical' game in extensive form that preserves all symmetries of the former one.
Bezalel Peleg +2 more
core
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Beyond Normal Form Invariance : First Mover Advantage in Two-Stage Games with or without Predictable Cheap Talk [PDF]
Von Neumann (1928) not only introduced a fairly general version of the extensive form game concept. He also hypothesized that only the normal form was relevant to rational play.
Hammond, Peter J.
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Normal Form in a Delay-Insensitive Algebra
A process algebra is given for specifying delay-insensitive processes. We show in two steps that expressions in this algebra have a normal form, as a consequence of which the algebra is complete.
Groenboom, R +3 more
core +1 more source
A Kind of Forest Disease and Pest Infection Model with Time Delay
Controlling forest diseases and insect pests is beneficial to increase forest carbon sink. It is of great significance to realize China ′s“ double carbon ”strategy.
FEI Xingyan, DING Yuting
doaj +1 more source
The author describes the idea of the construction of a certain normal form for terms of the language of Brouwerian semilattices, which goes back to \textit{V. A. Yankov} [Izv. Akad. Nauk SSSR, Ser. Mat. 33, 18-38 (1969; Zbl 0181.00404); translation in Math. USSR, Izv. 3, 15-35 (1969)].
openaire +3 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source

