Results 241 to 250 of about 2,502,460 (317)

Multivariate Bayesian Dynamic Borrowing for Repeated Measures Data With Application to External Control Arms in Open-Label Extension Studies. [PDF]

Biom J
Hartley BF, Psioda MA, Mander AP.
europepmc   +1 more source

A new normal form of Boolean functions

, 1976
Akio Odaka, Hiroaki Fujita, Susumu Nojima, Hiroshi Narushima   +3 more
openalex   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Perioperative Blood Management on a Successful Surgical Operation of a Patient With Congenital Coagulation Factor V Deficiency. [PDF]

Clin Case Rep
Shi R, Wu J, Meng Q, Nie J, Zhang L, Long X, Yang L, Zhao S.   +7 more
europepmc   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

The pleiotropic roles of non-hormonal receptor basigin and regulatory microRNAs in breast cancer. [PDF]

NPJ Breast Cancer
Bruce K, Kerin M, Richard V.
europepmc   +1 more source

Normal forms for real surfaces in C2 near complex tangents and hyperbolic surface transformations

, 1983
Jürgen Moser, S. M. Webster
openalex   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Fractional heat conduction with variable thermal conductivity in rotating hydro-semiconductors. [PDF]

Sci Rep
Elshazly IS, Alshormani F, El Nasr MA, El-Bary AA, Adel M, Jlali L, Lotfy K.   +6 more
europepmc   +1 more source