Results 151 to 160 of about 7,316,719 (298)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Abstraction Super-Structuring Normal Forms: Towards a Theory of Structural Induction. [PDF]
Algorithmic Probab Friends (2011), 2013 Silvescu A, Honavar V.
europepmc +1 more source
Normal Forms of the ODE System.
, 2000 : In a neighborhood of a stationary point we consider the n-dimensional autonomous formal system of ordinary differential equations. We give 5 types of normal forms (resonant, secondary, Belitskii, complete Belitskii, Gaeta), to which the ...
Petrovich V.Yu. http://library.keldysh.ru/author_page.asp?aid=1431 +1 more
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Diffusion times and stability exponents for nearly integrable analytic systems
Open Mathematics, 2005 Lochak Pierre, Marco Jean-Pierre
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Paradigm for the creation of scales and phases in nonlinear evolution equations
Electronic Journal of Differential Equations, 2023 Christophe Cheverry, Shahnaz Farhat
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source