Results 51 to 60 of about 18,119 (240)

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Profiling Co‐Occurrent Morphological Phenotypes and Their Degree of Expression Severity in Vacuolated Cells by Holo‐Tomographic Flow Cytometry and Fractal Analysis

Advanced Intelligent Systems, EarlyView.
HTFC gets 3D refractive index tomograms of flowing cells. Label‐free monocytes are engineered to express patterns of cytoplasmic vacuoles. From the tomogram, an efficient dimensionality reduction is operated. Interpretable features are extracted to classify the expression severity of phenotypes coexisting in each cell, visually represented by a seven ...
Marika Valentino, Giusy Giugliano, Daniele Pirone, Fabrizio Licitra, Fulvia Vitale, Pasquale Memmolo, Lisa Miccio, Massimo D’Agostino, Pietro Ferraro, Vittorio Bianco   +9 more
wiley   +1 more source

Validation of Soft Classification Models using Partial Class Memberships: An Extended Concept of Sensitivity & Co. applied to the Grading of Astrocytoma Tissues

, 2013
We use partial class memberships in soft classification to model uncertain labelling and mixtures of classes. Partial class memberships are not restricted to predictions, but may also occur in reference labels (ground truth, gold standard diagnosis) for ...
Beleites, Claudia, Salzer, Reiner, Sergo, Valter   +2 more
core   +1 more source

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

Animal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen, Xijia Shao, Xiulin Zhang, Ningning Zhang, Xiao Chen, Guangxin Yue, Jiangping Song   +6 more
wiley   +1 more source

Some Characterization of Normal Multi-fuzzy and Normal Multi-anti fuzzy Subgroup

IOSR Journal of Mathematics, 2014
This paper is mainly concerned with a generalization of the concept of a normal multi-fuzzy subgroup and a normal multi-anti fuzzy subgroup. We introduce the concept of a normal multi-fuzzy subgroup of a multi-fuzzy subgroup and examine its basic properties.
R. Muthuraj, S. Balamurugan
openaire   +1 more source

Coherence‐Gated Wrapped‐Phase InSAR With Matrix‐Based Uncertainty Diagnostics for Burial‐Mound Hotspot Ranking (Sicily, Italy)

Archaeological Prospection, EarlyView.
ABSTRACT Burial mounds are key elements of Mediterranean funerary landscapes, but in intensively cultivated coastal plains their low‐relief expression is easily obscured by ploughing, levelling and rapidly changing surface conditions, making single‐date observations unreliable.
Salvatore Polverino, Hourakhsh Ahmadnia, Rokhsaneh Rahbarianyazd Ahmadnia   +2 more
wiley   +1 more source

SUBIC: A Supervised Bi-Clustering Approach for Precision Medicine

, 2017
Traditional medicine typically applies one-size-fits-all treatment for the entire patient population whereas precision medicine develops tailored treatment schemes for different patient subgroups.
Levy, Phillip, Nezhad, Milad Zafar, Sadati, Najibesadat, Yang, Kai, Zhu, Dongxiao   +4 more
core   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Addressing Small Data Challenges in Biopharmaceutical Development and Manufacturing: A Mini Review of Multi‐Fidelity Techniques

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) models have the potential to accelerate this process, but their success depends on access to large
Mohammad Golzarijalal, Uwe Aickelin, Ellen Otte   +2 more
wiley   +1 more source

Rough matroids based on coverings [PDF]

, 2013
The introduction of covering-based rough sets has made a substantial contribution to the classical rough sets. However, many vital problems in rough sets, including attribution reduction, are NP-hard and therefore the algorithms for solving them are ...
Yang, Bin, Zhao, Hong, Zhu, William
core