Results 41 to 50 of about 1,366,906 (287)

Normal and normally outer automorphisms of free metabelian nilpotent Lie algebras [PDF]

open access: yes, 2010
Let L be the free m-generated metabelian nilpotent of class c Lie algebra over a field of characteristic 0. An automorphism f of L is called normal if f(I)=I for every ideal I of the algebra L.
Findik, Sehmus
core   +1 more source

Higher homotopy of groups definable in o-minimal structures

open access: yes, 2009
It is known that a definably compact group G is an extension of a compact Lie group L by a divisible torsion-free normal subgroup. We show that the o-minimal higher homotopy groups of G are isomorphic to the corresponding higher homotopy groups of L.
Berarducci, Alessandro   +2 more
core   +2 more sources

Totally disconnected locally compact groups with a linear open subgroup [PDF]

open access: yes, 2014
We describe the global structure of totally disconnected locally compact groups having a linear open compact subgroup. Among the applications, we show that if a non-discrete, compactly generated, topologically simple, totally disconnected locally compact
Caprace, Pierre-Emmanuel   +1 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle   +5 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

T4 rather than TSH correlates with BMD among euthyroid adults

open access: yesFrontiers in Endocrinology, 2023
PurposeThe objective of this study was to evaluate the association between thyroid hormone and bone mineral density (BMD) among euthyroid adults.MethodsThis cross-sectional study researched the information from the National Health and Nutrition ...
Ning Sheng   +4 more
doaj   +1 more source

Genome-scale analysis of aberrant DNA methylation in colorectal cancer.

open access: yesGenome Research, 2012
Colorectal cancer (CRC) is a heterogeneous disease in which unique subtypes are characterized by distinct genetic and epigenetic alterations. Here we performed comprehensive genome-scale DNA methylation profiling of 125 colorectal tumors and 29 adjacent ...
T. Hinoue   +11 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Association of gestational diabetes mellitus diagnosed at different time points in oral glucose tolerance test with adverse pregnancy outcomes: a retrospective cohort study

open access: yesFrontiers in Endocrinology
BackgroundThis study aims to explore the association between gestational diabetes mellitus (GDM) diagnosed at different time points in the oral glucose tolerance test (OGTT) and adverse pregnancy outcomes (APO).MethodsA retrospective cohort study based ...
Ruipeng Lin   +7 more
doaj   +1 more source

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