Results 71 to 80 of about 1,366,906 (287)

The relation between the blood glucose level and the FDG uptake of tissues at normal PET examinations

open access: yesEJNMMI Research, 2013
BackgroundThe influence of the blood glucose level on the tracer uptake of normal tissues at [18F]-2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) was retrospectively studied in examinations in clinical patients.MethodsFive hundred ...
H. Lindholm   +3 more
semanticscholar   +1 more source

Nonarchimedean superrigidity of solvable S-arithmetic groups

open access: yes, 2014
Let Gamma be an S-arithmetic subgroup of a solvable algebraic group G over an algebraic number field F, such that the finite set S contains at least one place that is nonarchimedean.
Morris, Dave Witte, Studenmund, Daniel
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

One-relator groups with torsion are conjugacy separable

open access: yes, 2012
We prove that one-relator groups with torsion are hereditarily conjugacy separable. Our argument is based on a combination of recent results of Dani Wise and the first author.
Minasyan, Ashot, Zalesskii, Pavel
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Efficacy of Ixekizumab in Chinese Patients with Radiographic Axial Spondyloarthritis by Baseline C-Reactive Protein Level

open access: yesRheumatology and Therapy
Introduction Ixekizumab, an interleukin 17A inhibitor, improved the Assessment of SpondyloArthritis international Society 40 (ASAS40) response rates irrespective of baseline inflammation in international populations with radiographic axial ...
Ning Kong   +14 more
doaj   +1 more source

Proaterogenic disorders of lipid and carbohydrate metabolism in chronic kidney disease nondiabetic origin

open access: yesZaporožskij Medicinskij Žurnal, 2013
Purpose. Identify the features of lipid and carbohydrate metabolism, state of lipid peroxidation (LPO) in patients with chronic kidney disease (CKD) nondiabetic origin depending on the degree of renal dysfunction. Materials and methods.
T. N. Solomenchuk, H. V Semegen-Bodak
doaj   +1 more source

Features and outcome of AIH patients without elevation of IgG

open access: yesJHEP Reports, 2020
Background & Aims: High IgG levels are considered a hallmark of autoimmune hepatitis (AIH). A subgroup of patients with AIH has IgG within the normal range despite evidence of clinical disease activity. The clinical significance of this biomarker has
Johannes Hartl   +17 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy