Results 71 to 80 of about 1,366,906 (287)
BackgroundThe influence of the blood glucose level on the tracer uptake of normal tissues at [18F]-2-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) was retrospectively studied in examinations in clinical patients.MethodsFive hundred ...
H. Lindholm +3 more
semanticscholar +1 more source
Nonarchimedean superrigidity of solvable S-arithmetic groups
Let Gamma be an S-arithmetic subgroup of a solvable algebraic group G over an algebraic number field F, such that the finite set S contains at least one place that is nonarchimedean.
Morris, Dave Witte, Studenmund, Daniel
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
One-relator groups with torsion are conjugacy separable
We prove that one-relator groups with torsion are hereditarily conjugacy separable. Our argument is based on a combination of recent results of Dani Wise and the first author.
Minasyan, Ashot, Zalesskii, Pavel
core +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Introduction Ixekizumab, an interleukin 17A inhibitor, improved the Assessment of SpondyloArthritis international Society 40 (ASAS40) response rates irrespective of baseline inflammation in international populations with radiographic axial ...
Ning Kong +14 more
doaj +1 more source
Purpose. Identify the features of lipid and carbohydrate metabolism, state of lipid peroxidation (LPO) in patients with chronic kidney disease (CKD) nondiabetic origin depending on the degree of renal dysfunction. Materials and methods.
T. N. Solomenchuk, H. V Semegen-Bodak
doaj +1 more source
Features and outcome of AIH patients without elevation of IgG
Background & Aims: High IgG levels are considered a hallmark of autoimmune hepatitis (AIH). A subgroup of patients with AIH has IgG within the normal range despite evidence of clinical disease activity. The clinical significance of this biomarker has
Johannes Hartl +17 more
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source

