Results 41 to 50 of about 116,171 (310)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Frontiers in Human Neuroscience, 2018 People are strongly motivated to pursue social equality during social interactions. Previous studies have shown that outcome equality influences the neural activities of monetary feedback processing in socioeconomic games; however, it remains unclear ...
Changquan Long +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Adapting Recommendation Diversity to Openness to Experience : A Study of Human Behaviour [PDF]
, 2013 . This paper uses a User-as-Wizard approach to evaluate how people apply diversity to a set of recommendations. In particular, it con-siders how diversity is applied for a recipient with high or low Openness to Experience, a personality trait from the ...
Nava Tintarev +5 more
core +1 more source
Frontiers in Psychology, 2017 Attentional bias toward negative stimuli has been observed in major depression disorders (MDDs). Imaging studies suggest the engagement of fronto-limbic regions like amygdala, anterior cingulate cortex (ACC), and lateral prefrontal cortex, is related to ...
Haijiang Li +8 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2015 We assessed normal personality traits and childhood trauma in approximately 1170 subjects from a general population-based community sample. In bivariate analyses emotional abuse was most pervasively related to personality, showing significant detrimental
Cohen, Lisa J. +11 more
core +1 more source
Perfectionism and the Big Five: Conscientiousness predicts longitudinal increases in self-oriented perfectionism [PDF]
, 2009 Findings from cross-sectional studies on the relationship between perfectionism and the Big Five personality traits demonstrate that conscientiousness shows significant positive correlations with self-oriented perfectionism, and neuroticism with socially
Stoeber, Joachim +2 more
core +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Perfectionism and aptitude test performance: Testees who strive for perfection achieve better test results [PDF]
, 2007 Positive conceptions of perfectionism (Stoeber & Otto, 2006) suggest that perfectionistic strivings may form part of a healthy pursuit of excellence and are associated with higher academic achievement and higher performance in laboratory tasks. To extend
Stoeber, Joachim +2 more
core +1 more source