Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim +16 more
wiley +1 more source
Quality of life in women with normal pregnancy. [PDF]
Wójcik M, Aniśko B, Siatkowski I.
europepmc +1 more source
Consecutive reference intervals for biochemical indices related to serum lipid levels and renal function during normal pregnancy. [PDF]
Wu L +6 more
europepmc +1 more source
The Role of Decidual Macrophages During Normal and Pathological Pregnancy
F. Ning, Huishu Liu, G. Lash
semanticscholar +1 more source
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen +12 more
wiley +1 more source
A Hypoxia-Decidual Macrophage Regulatory Axis in Normal Pregnancy and Spontaneous Miscarriage. [PDF]
Huang X +7 more
europepmc +1 more source
The Role of Fatty Acid Signaling in Islet Beta-Cell Adaptation to Normal Pregnancy. [PDF]
Kim JH +5 more
europepmc +1 more source
The renal circulation in normal pregnancy and preeclampsia: is there a place for relaxin?
K. Conrad, J. Davison
semanticscholar +1 more source
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi +10 more
wiley +1 more source
Cervical Collagen Network Porosity Assessed by SHG Endomicroscopy Distinguishes Preterm and Normal Pregnancy-A Pilot Study. [PDF]
Liang W +6 more
europepmc +1 more source

