Results 141 to 150 of about 50,587 (257)

From Molecule to Meaning: Neuronopathic Biomarkers and Clinical Relevance in GM1

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT GM1 gangliosidosis is a rare, progressively neurodegenerative lysosomal storage disorder characterized by profound central nervous system involvement and substantial clinical heterogeneity. The development of reliable biomarkers is essential for tracking disease progression, stratifying patients, and advancing clinical trial readiness. Primary
Krista Casazza, Roberto Giugliani, Debra S. Regier, Jeanine Jarnes   +3 more
wiley   +1 more source

Homonymous hemianopsia as a reversible manifestation of normal-pressure hydrocephalus [PDF]

, 2021
Jason Zehden, Subahari Raviskanthan, Nita Bhat, Peter W. Mortensen, Gustavo C. Román, Andrew G. Lee   +5 more
openalex   +1 more source

The Boy Who Grew a New Brain: Understanding this Miracle from a Neuro-Quantum Perspective [PDF]

, 2018
In this paper, we present a case of a boy – Noah Wall, who till today surprises the world of neuroscience with his will to grow his brain and survive.
Pereira, Contzen, Reddy, Jumpal Shashi Kiran   +1 more
core  

A Nonketotic Hyperglycinemia Mouse Shows Wide‐Ranging Biochemical Consequences of Elevated Glycine, Reduced Folate One‐Carbon Charging, and Serine Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Nonketotic hyperglycinemia is a severe neonatal epileptic encephalopathy caused by deficient glycine cleavage enzyme activity, for which currently no effective treatment exists. Incomplete understanding of brain biochemistry represents a major knowledge gap to develop new treatments.
Michael A. Swanson, Hua Jiang, Lakshmi Divya Kolora, Rachel Molino, Richard Reisdorph, Cole R. Michel, Katrina A. Doenges, Kit‐Yi Leung, Xiangping Lin, Frank Wong, Samual Lancaster, Basil Michael, Michael Snyder, Daniella H. Hock, David A. Stroud, Tim Wood, Robert Binard, Laura Anderson‐Lehman, Uwe Christians, Erland Arning, Marisa W. Friederich, Roxanne A. Van Hove, Kenneth N. MacLean, Nicholas D. E. Greene, Johan L. K. Van Hove   +24 more
wiley   +1 more source

Idiopathic Intracranial Hypertension—Clinical Characteristics, Neuroimaging and Outcome of Patients from Pretoria, South Africa

Neurology and Clinical Neuroscience, Volume 14, Issue 1, Page 46-53, January 2026.
ABSTRACT Background Idiopathic intracranial hypertension is a syndrome characterized by symptoms and signs of raised intracranial pressure without a secondary cause. It primarily affects young obese women who present with headache and papilledema. We report the clinical presentation, brain imaging findings and outcomes of patients with IIH from two ...
Bandlakazi Sukwana‐Ncemane, Juliane Hiesgen, Clara M. Schutte   +2 more
wiley   +1 more source

Syndrome of Inappropriate Secretion of Antidiuretic Hormone in a Dog With Meningoencephalitis of Unknown Etiology

Veterinary Medicine and Science, Volume 12, Issue 1, January 2026.
This report describes a case of syndrome of inappropriate antidiuretic hormone secretion (SIADH) in a Maltese with meningoencephalitis of unknown etiology (MUE). The dog was treated with water restriction and tolvaptan, a vasopressin receptor antagonist, which resulted in an improvement in hyponatremia.
Yelim Lee, Jooyoung Park, Yeon Chae, Taesik Yun, Hakhyun Kim, Byeong‐Teck Kang   +5 more
wiley   +1 more source

Implementation of CSF flow dynamic assessment with phase-contrast MRI in the diagnostic process of idiopathic normal pressure hydrocephalus

, 2023
Serena Cole, Pan Liu, K. P. Owashi, Benjamin Dias Dougan, Tomasz Matys, Peter Smielewski, Olivier Balédent, Alexis Joannides   +7 more
openalex   +1 more source

Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome

Academic Emergency Medicine, Volume 33, Issue 1, January 2026.
ABSTRACT Study Objective Treatment strategies in severe hyponatremia aim at rapid sodium correction to prevent or treat cerebral edema but limit sodium rise to prevent osmotic demyelination syndrome (ODS). The true risk of edema or ODS in ED patients is unknown.
Volker Burst, Ramon Rabii, Julian Peto‐Madew, Thorsten Persigehl, Stefan Haneder, Matthias Johannes Hackl, Christoph Hüser, Moritz Trappe, Sadrija Cukoski, Kathrin Möllenhoff, Victor Suárez   +10 more
wiley   +1 more source

The Use of Combined Fundus Photography and Perimetry for the Assessment of Patients Referred for Intracranial Hypertension or Follow‐Up of the Diagnosis in a Tertiary Headache Center

European Journal of Neurology, Volume 33, Issue 1, January 2026.
ABSTRACT Objectives Idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure and papilledema. If left untreated, it can lead to vision loss, and, timely detection of papilledema is of paramount importance. Direct ophthalmoscopy can be difficult to perform and interpret for non‐ophthalmologists.
Zainab Rissan, Nadja Skadkær Hansen, Vlasta Vukovic‐Cvetkovic, Louise Ninett Carlsen, Steffen Hamann, Marianne Wegener, Rigmor H. Jensen, Henrik Winther Schytz   +7 more
wiley   +1 more source

Laparoscopically guided ventriculoperitoneal drainage placement for the treatment of normal pressure hydrocephalus–a report of a case and surgical technique

Zdravniški Vestnik, 2012
Ventriculoperitoneal drainage is a widely accepted technique for the management of normal pressure hydrocephalus. With the advent of minimally invasive techniques, laparoscopy is being increasingly used for shunt placement.
Tomaž Velnar, Franc Jelenc, Marjan Koršič   +2 more
doaj