Results 81 to 90 of about 167,118 (284)
Background Little is known about the epidemiology of stroke in chronic systolic and diastolic heart failure (HF) patients in normal sinus rhythm (NSR) receiving angiotensin-converting enzyme (ACE) inhibitors.
M. Mujib +9 more
semanticscholar +1 more source
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
Update on the Pathophysiology, Aetiology and Management of Central Sleep Apnoea
ABSTRACT Central sleep apnoea (CSA) of the periodic breathing type occurs during the transition between wakefulness and stage 1 and 2 non‐REM sleep. In adults at sea level, it occurs most commonly due to advanced heart failure (HF) or chronic opioid use and in ~5% of obstructive sleep apnoea patients initiating CPAP.
Sahan D. Chandrasekara +1 more
wiley +1 more source
Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang +16 more
wiley +1 more source
A 32-year-old man underwent catheter ablation of an orthodromic atrioventricular reentrant tachycardia. The sinus rhythm electrocardiogram exhibited a normal PQ interval and no delta waves, but atrial pacing produced a prolonged PQ interval and wide QRS ...
Kohki Nakamura, MD +3 more
doaj +1 more source
Abstract Abnormalities in the heart's rhythm, known as arrhythmias, pose a significant threat to global health, often leading to severe cardiac conditions and sudden cardiac deaths. Therefore, early and accurate detection of arrhythmias is crucial for timely intervention and potentially life‐saving treatment.
Hasnain Ali Shah +4 more
wiley +1 more source
Intra‐ and Interspecific Effects on Spatio‐Temporal Behavior of Common Commensal Rodent Species
This study revealed major findings on spatio‐temporal behavior of commensal rodents on a pig farm showing the influence of interspecific dominance on movement behavior and the resulting species‐specific ecological adaptations. Additionally, rodents tend to stay in their home ranges and migration to other stable buildings is only rare.
Florian Huels +8 more
wiley +1 more source
Shortening of ventriculoatrial interval after ablation of an accessory pathway
A 21-year old man with history of 8 year palpitation was referred for electrophysiologic study and possible radiofrequency ablation. Physical examination and transthoracic echocardiographic study did not disclose any abnormality.
Mohammad Alasti +4 more
doaj
Abstract Purpose Physiological pulsations driven by cardiac, respiratory, and vasomotor activity are essential for solute transport within perivascular and perineural cerebrospinal fluid (CSF) pathways that support brain and eye clearance systems. Previous studies have shown that parasympathetic blockade significantly reduces ocular pulsation power and
Ebrahimi Seyed‐Mohsen +9 more
wiley +1 more source

