Results 51 to 60 of about 353,915 (269)

Mixed and Non-mixed Normal Subgroups of Dihedral Groups Using Conjugacy classes

open access: yesRatio Mathematica, 2021
In this paper, we characterize and compute the mixed and non-mixed basis of Dihedral groups. Also, by computing the conjugacy classes, we describe all the mixed and non-mixed normal subgroups of Dihedral Groups.
S. Vinod, G.S. Biju
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Morphisms of Mislin genera induced by finite normal subgroups

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2002
We correct an erroneous statement about induced morphisms of Mislin genera and give the correct statement, even under more general hypotheses.
P. J. Hilton, P. J. Witbooi
doaj   +1 more source

Groups with many Subgroups which are Commensurable with some Normal Subgroup [PDF]

open access: yesAdvances in Group Theory and Applications, 2019
A subgroup H of a group G is called commensurable with a normal subgroup (cn) if there is N C G such that |HN/(H ∩ N)| is finite. We characterize generalized radical groups G which have one of the following finiteness conditions: (A) the minimal ...
Ulderico Dardano, Silvana Rinauro
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Normalizers and self-normalizing subgroups

open access: yesGlasnik matematicki, 2011
Let $\mathbb K$ be a field of characteristic $\neq 2$. Suppose $G=\boldsymbol{; ; G}; ; (\mathbb K)$ is the group of $\mathbb K$-points of a reductive algebraic $\mathbb K$-group $\boldsymbol{; ; G}; ; $. Let $G_1\leq G$ be the group of $\mathbb K$-points of a reductive subgroup $\boldsymbol{; ; G}; ; _1\leq \boldsymbol{; ; G}; ; $.
openaire   +5 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Algebraic structure of some complex intuitionistic fuzzy subgroups and their homomorphism

open access: yesAIMS Mathematics
The complex fuzzy environment is an innovative tool to deal with fuzzy situations in different mathematical problems. Aiming at the concept of complex intuitionistic fuzzy subgroups, this paper has introduced cut-subsets of complex intuitionistic fuzzy ...
Zhuonan Wu, Zengtai Gong
doaj   +1 more source

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