Results 151 to 160 of about 63,918 (292)

N‐Lactoyl Amino Acids: Emerging Biomarkers in Metabolism and Disease

open access: yesDiabetes/Metabolism Research and Reviews, Volume 41, Issue 5, July 2025.
ABSTRACT N‐lactoyl amino acids (Lac‐AA) form an emerging class of metabolites that have gained significant attention in recent years due to their ubiquitous presence in different biological systems and potential roles in various biochemical processes. This narrative review aims to provide a comprehensive overview of the current understanding of Lac‐AA,
Khaled Naja   +4 more
wiley   +1 more source

Pesquisaje de glaucoma

open access: yesRevista Cubana de Medicina General Integral, 1996
Se efectuó un pesquisaje de glaucoma mediante un chequeo masivo al 92,1 % (210 pacientes) de la población mayor de 40 años de edad atendida en un consultorio del médico de la familia del municipio Morón.
Aldo Sigler Villanueva   +5 more
doaj  

Targeting Connexin 43 in Retinal Astrocytes Promotes Neuronal Survival in Glaucomatous Injury

open access: yesGlia, Volume 73, Issue 7, Page 1398-1419, July 2025.
Main Points Astrocytes play an important role in glaucoma. These cells express Cx43 which can form gap junctions and hemichannels. This study shows Cx43 deletion in astrocytes provides neuroprotection in glaucoma, possibly through hemichannel activation.
Khulan Batsuuri   +4 more
wiley   +1 more source

Oxidative Stress: Signaling Pathways, Biological Functions, and Disease

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu   +4 more
wiley   +1 more source

Downregulation of USP9X in the DG Region of the Hippocampus Leads to AD‐Like Cognitive Dysfunction in Mice

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Experimental procedures at the animal and cell levels in this study. ABSTRACT Objective This study investigates the link between ubiquitin‐specific peptidase 9 X‐linked (USP9X) and Alzheimer's disease (AD) pathogenesis, aiming to identify potential targets for AD diagnosis, treatment, and drug development.
Xiaochuan Qi   +7 more
wiley   +1 more source

The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma [PDF]

open access: bronze, 2007
Takayuki Harada   +10 more
openalex   +1 more source

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