Results 101 to 110 of about 326,945 (325)

Un nouveau test d’évaluation de la biodégradabilité dans le sol -- Travaux de normalisation en cours

open access: yesOléagineux, Corps gras, Lipides, 2003
Biodégradabilité primaire (disparition d’un composé parent), biodégradabilité ultime (stade terminal de la transformation du composé), écotoxicité, bio-accumulation autant d’outils à notre disposition pour évaluer l’impact environnemental des composés ...
Cecutti Christine
doaj   +1 more source

Lexical Normalisation of Twitter Data

open access: yes, 2015
Twitter with over 500 million users globally, generates over 100,000 tweets per minute . The 140 character limit per tweet, perhaps unintentionally, encourages users to use shorthand notations and to strip spellings to their bare minimum "syllables" or ...
Ahmed, Bilal
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Forward Physics at the LHC [PDF]

open access: yes, 2008
The CMS/TOTEM and ATLAS collaborations carry out a program of forward physics with several near-beam detectors extending their coverage to high pseudorapidities.
Rouby, Xavier
core   +1 more source

Refocusing Generalised Normalisation [PDF]

open access: yes, 2007
When defined with general elimination/application rules, naturaldeduction and λ-calculus become closer to sequentcalculus. In order to get real isomorphism, normalisation has to bedefined in a "multiary" variant, in which reduction rules arenecessarily non-local (reason: nomalisation, like cut-elimination,acts at the headof applicative terms, but ...
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Journalistic “Innovation” Is Hard to Hate, but Actual Change Is Just Hard

open access: yesMedia and Communication
Who is opposed to “innovation”? For most newsroom publishers, managers, editors, and reporters, the word connotes progress; it implies a strategy for achieving success—and dodging failure.
Jane B. Singer
doaj   +1 more source

Home - About - Disclaimer - Privacy