Results 211 to 220 of about 326,945 (325)

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

EcoCondition Toolset - A QGIS plugin for ecosystem condition assessments. [PDF]

MethodsX
Valença Pinto L, Inácio M, Santos-Martín F, Burkhard B, Pereira P.   +4 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Der nonkonforme Blick. Ivan Kyncls Fotografien der tschechoslowakischen Gesellschaft in der Zeit der „Normalisierung“

Zeithistorische Forschungen, 2011
Heidrun Hamersky
doaj   +1 more source

Rupture ou normalisation?

, 2017
Parler du judaïsme en Espagne, c’est pour la plupart des gens parler d’une question plus mythique que réelle, bien que, lors des xxe et xxie siècles, la présence de la population juive en Espagne ait augmenté et soit devenue plus visible. Cette absence du judaïsme contemporain dans l’imaginaire collectif se retrouve également dans le champ académique ...
openaire   +2 more sources

P-21 Kinase 1 or 4 Knockout Stimulated Anti-Tumour Immunity Against Pancreatic Cancer by Enhancing Vascular Normalisation. [PDF]

Int J Mol Sci
Ansardamavandi A, Dumesny C, Ma Y, Dong L, Ellis S, Ang CS, Nikfarjam M, He H.   +7 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

CHILDHOOD - ADOLESCENCE - DEMOCRACY. CONTINGENCY, LOSS AND NORMALISATION OF THE PHENOMENON OF ADOLESCENCE IN MODERN SOCIETIES (Dziecinstwo-mlodosc-demokracja. Kontyngencja, zanik i normalizacja fenomenu mlodziezy w spoleczenstwach nowoczesnych)

, 2011
Dietrich Benner, Dariusz Stępkowski
openalex   +1 more source

Liquid Biopsy in Clear Cell Renal Cell Carcinoma: Diagnostic Potential of Urinary miRNAs. [PDF]

Cancers (Basel)
Vannuccini G, Paladini A, Mearini M, Cocci F, Giardino G, Mangione P, Maulà V, Mirra D, Mearini E, Cochetti G.   +9 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source