Results 111 to 120 of about 155,801 (328)

Identifying Stable Reference Genes for qRT-PCR Normalisation in Gene Expression Studies of Narrow-Leafed Lupin (Lupinus angustifolius L.)

PLoS ONE, 2016
Quantitative Reverse Transcription PCR (qRT-PCR) is currently one of the most popular, high-throughput and sensitive technologies available for quantifying gene expression.
Candy M. Taylor, Ricarda Jost, W. Erskine, M. Nelson   +3 more
semanticscholar   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Identifying Research Fields within Business and Management: A Journal Cross-Citation Analysis [PDF]

, 2012
A discipline such as business and management (B&M) is very broad and has many fields within it, ranging from fairly scientific ones such as management science or economics to softer ones such as information systems.
Hair J, John Mingers, Loet Leydesdorff, Mingers J, Salton G, Van Raan A   +5 more
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Garside and quadratic normalisation: a survey [PDF]

, 2015
Starting from the seminal example of the greedy normal norm in braid monoids, we analyse the mechanism of the normal form in a Garside monoid and explain how it extends to the more general framework of Garside families. Extending the viewpoint even more,
A Cain, D Bessis, D Krammer, E Artin, E Brieskorn, EA El-Rifai, FA Garside, J Birman, J Cassaigne, JM Howie, L Bokut, M Hoffmann, P Dehornoy, P Dehornoy, P Dehornoy, P Dehornoy, P Dehornoy, R Charney   +17 more
core   +1 more source

Selection of Novel Reference Genes by RNA-Seq and Their Evaluation for Normalising Real-Time qPCR Expression Data of Anthocyanin-Related Genes in Lettuce and Wild Relatives [PDF]

, 2023
Inés Medina‐Lozano, María Soledad Arnedo, Jérôme Grimplet, Aurora Díaz   +3 more
openalex   +1 more source

Optimising impact and sustainability: a qualitative process evaluation of a complex intervention targeted at compassionate care

BMJ Quality & Safety, 2017
Background Despite concerns about the degree of compassion in contemporary healthcare, there is a dearth of evidence for health service managers about how to promote compassionate healthcare.
J. Bridges, C. May, A. Fuller, P. Griffiths, W. Wigley, Lisa Gould, H. Barker, P. Libberton   +7 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Chern-Simons Theory on S^1-Bundles: Abelianisation and q-deformed Yang-Mills Theory

, 2006
We study Chern-Simons theory on 3-manifolds $M$ that are circle-bundles over 2-dimensional surfaces $\Sigma$ and show that the method of Abelianisation, previously employed for trivial bundles $\Sigma \times S^1$, can be adapted to this case.
C. Beasley, C. Vafa, D. Jafferis, George Thompson, J. Martinet, M. Aganagic, M. Blau, Matthias Blau, N. Berline, N. Caporaso ., N. Caporaso ., R. Bott, S. de Haro   +12 more
core   +3 more sources

Evaluating a clinical ethics committee (CEC) implementation process in an oncological research hospital: protocol for a process evaluation study using normalisation process theory (EvaCEC) [PDF]

, 2023
Marta Perin, Morten Magelssen, Luca Ghirotto, Ludovica De Panfilis   +3 more
openalex   +1 more source