Results 141 to 150 of about 20,046 (252)

RNAdvisor 2: A unified platform for RNA 3D model quality assessment using metrics, scoring functions, and meta-metrics. [PDF]

Sci Rep
Bernard C, Postic G, Ghannay S, Tahi F.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Smart system for forecasting financial outcomes and supporting strategic choices. [PDF]

Sci Rep
Lang F, Liu Y.
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Using normalisation process theory to evaluate the implementation of a digital health intervention in community and secondary care long COVID clinics [PDF]

Fiona Stevenson, Paul Pfeffer, Sarah Walker, Hadiza Ismaila, Veeriah Jegatheesan, Ibrahim Mohammad, Ann Blandford, Stuart Linke, John R. Hurst, William Ricketts, Fiona Hamilton, David Sunkersing, Katherine Bradbury, Henry Goodfellow   +13 more
openalex   +1 more source

Bringing the Discussion of Minima Sharpness to the Audio Domain: A Filter-Normalised Evaluation for Acoustic Scene Classification

, 2023
Manuel Milling, Andreas Triantafyllopoulos, Iosif Tsangko, Simon Rampp, Björn W. Schuller   +4 more
openalex   +2 more sources

Artificial intelligence based quantification of T lymphocyte infiltrate predicts prognosis in high grade breast cancer using deep learning and statistical validation. [PDF]

Discov Oncol
Albalawi ES, Qayyum J, Qayyum J.
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

CMR evaluation of diastolic function impairment in Cushing’s syndrome and its normalisation with treatment

, 2015
Charles Roux
openalex   +1 more source

Evaluation of normalisation strategies for qPCR data obtained from canine gastrointestinal tissues with different pathologies. [PDF]

Sci Rep
Luigi-Sierra MG, Lyngby JG, Ingerslev AS, Jacobsen JM, Nielsen LN, Cirera S.   +5 more
europepmc   +1 more source