Results 181 to 190 of about 155,801 (328)

An EWS-LSTM-Based Deep Learning Early Warning System for Industrial Machine Fault Prediction

Applied Sciences
Early warning systems (EWSs) are crucial for optimising predictive maintenance strategies, especially in the industrial sector, where machine failures often cause significant downtime and economic losses. This research details the creation and evaluation
Fabio Cassano, Anna Maria Crespino, Mariangela Lazoi, Giorgia Specchia, Alessandra Spennato   +4 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Exploring the scope for Normalisation Process Theory to help evaluate and understand the processes involved when scaling up integrated models of care: a case study of the scaling up of the Gnosall memory service [PDF]

, 2020
Michael Clark, David Jolley, Susan Benbow, Nicola Greaves, Ian Greaves   +4 more
openalex   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

On the Quasi-Hopf structure of deformed double Yangians

, 2000
We construct universal twists connecting the centrally extended double Yangian DY(sl(2))_c with deformed double Yangians DY_r(sl(2))_c, thereby establishing the quasi-Hopf structures of the latter.Comment: 11 ...
Arnaudon, D., Avan, J., Frappat, L., Ragoucy, E., Rossi, M.   +4 more
core   +2 more sources

Co-designing organisational improvements and interventions to increase inpatient activity in four stroke units in England: a mixed-methods process evaluation using normalisation process theory [PDF]

, 2021
David Clarke, Karolina Gombert, Stephanie Honey, Geoffrey Cloud, Ruth Harris, Alastair Macdonald, Christopher McKevitt, Glenn Robert, Fiona Jones   +8 more
openalex   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

RETurn to work After stroKE (RETAKE) Trial: protocol for a mixed-methods process evaluation using normalisation process theory [PDF]

, 2022
Kate Radford, Christopher McKevitt, Sara Clarke, Katie Powers, Julie Phillips, Kristelle Craven, Caroline Watkins, Amanda Farrin, Jain Holmes, Rachel Cripps, Vicki McLellan, Tracey Sach, Richard Brindle, Ivana Holloway, Suzanne Hartley, Audrey Bowen, Rory J O’Connor, Judith Stevens, Marion Walker, J. Clifford Murray, Angela Shone, David Clarke   +21 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

The growth of international collaboration: Collaboration Category Normalised Citation Impact (Collab CNCI) and implications for responsible research evaluation [PDF]

, 2023
Ross W. K. Potter
openalex   +1 more source