Results 131 to 140 of about 751,319 (360)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
"For me it's just normal" - Strategies of children and young people from rainbow families against de-normalization. The case of Slovenia and Germany. [PDF]
Družboslovne Razprave, 2013 The paper presents some findings from an international study called “School is out – Experiences of children from rainbow families in school” which explored how children and young people from rainbow families anticipate, experience and deal with schools ...
Uli Streib Brzič, Ana M. Sobočan
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A decomposition of normality via a generalization of $\kappa$-normality
, 2017 A simultaneous generalization of $\kappa$-normality and weak $\theta$-normality is introduced. Interrelation of this generalization of normality with existing variants of normality is studied.In the process of investigation a new decomposition of ...
Pratibha Bhat +3 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
On Normality VIA Conditional Normality
, 1986 Consider X=( Xo , X1 ... , Xp) and suppose [Formula: see text] Assume further that Xi's ( i=0,1, ... , p) are marginally identically distributed. Does this Imply normality of X ?
Bikas K. Sinha, M. Ahsanullah
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Normality Testing- A New Direction
This paper is concerned with the evaluation of the performance of the normality tests to ensure the validity of the t-statistics used for assessing significance of regressors in a regression model.
Islam, Tanweer ul
core
A power comparison of various normality tests
, 2017 The assumption of normality is very important because it is used in many statistical procedures such as Analysis of variance, linear regression analysis, discriminant analysis and t-tests. The three common procedures are used for assessing the assumption
Fiaz Ahmad, R. Khan
semanticscholar +1 more source