Results 241 to 250 of about 1,289,600 (290)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Rectal Columns of Morgagni on X-ray: A Rarely Seen Normality.

open access: yesJ Indian Assoc Pediatr Surg
Siyol PL, Yhoshu E, Kashiv S, Balija SS.
europepmc   +1 more source

Normality of sagittal spinal alignment parameters reveals evolutionary signals in healthy adults across five countries. [PDF]

open access: yesSci Rep
Hasegawa K   +12 more
europepmc   +1 more source

Calculation of reference intervals using an indirect approach from laboratory database. [PDF]

open access: yesAdv Lab Med
Martin-Riera V   +13 more
europepmc   +1 more source

Distribution Analysis of the Lifespan Trait in Drosophila. [PDF]

open access: yesInt J Mol Sci
Yumuhova CA   +3 more
europepmc   +1 more source

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