Results 91 to 100 of about 3,802,566 (313)

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

open access: yes
Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi   +13 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Testing for Non-Normality in the Presence of One-Sided Slope Parameters [PDF]

open access: yes
In a recent paper, Hughes (1999) showed that the power of tests of linear regression parameters could be improved by utilizing one-sided information regarding the nuisance parameters in the testing problem.
Anthony W. Hughes
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Statistical Approaches Based on Deep Learning Regression for Verification of Normality of Blood Pressure Estimates

open access: yesSensors, 2019
Oscillometric blood pressure (BP) monitors currently estimate a single point but do not identify variations in response to physiological characteristics.
Soojeong Lee   +2 more
doaj   +1 more source

PSYNDEX Tests Review für WAW - WÜRFELABWICKLUNGEN

open access: yes, 1984
This is a PSYNDEX Tests Review of WAW - WÜRFELABWICKLUNGEN. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries. PSYNDEX Tests is offered by the Leibniz Institute
Lukesch, Helmut
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

PSYNDEX Tests Review für AZT - Abzeichentest

open access: yes, 1984
This is a PSYNDEX Tests Review of AZT - Abzeichentest. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Lukesch, Helmut
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

PSYNDEX Tests Review für TT - TOKEN TEST

open access: yes, 1982
This is a PSYNDEX Tests Review of TT - TOKEN TEST. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Orgaß, Bernt
core   +1 more source

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