Results 91 to 100 of about 331,728 (261)
In the paper, with the aid of a derivative formula for the ratio of two differentiable functions, in view of a monotonicity rule for the ratio of two differentiable functions, in terms of the Hessenberg determinants, the authors present a Maclaurin power series expansion of the logarithm of the normalized remainder of the Maclaurin power series ...
Fei Wang, Feng Qi
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Understanding how the dynamics of vegetation growth respond to climate change at different temporal and spatial scales is critical to projecting future ecosystem dynamics and the adaptation of ecosystems to global change.
Guang Xu +9 more
doaj +1 more source
Geometry of the sample frequency spectrum and the perils of demographic inference
The sample frequency spectrum (SFS), which describes the distribution of mutant alleles in a sample of DNA sequences, is a widely used summary statistic in population genetics.
Bhaskar, Anand +3 more
core +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Evaluation of bleeding risk in patients with renal impairment treated with Fondaparinux (Arixtra)
Background: Fondaparinux (Arixtra) a synthetic pentasaccharide that causes an antithrombin III-mediated selective inhibition of factor Xa. The clearance of fondaparinux reduces in patients with renal impairment, and there are no dosage adjustments ...
Hend H Metwali +6 more
doaj +1 more source
Scaling of the diffusion coefficient on the normal form remainder in doubly resonant domains
To appear in the proceedings of the international workshop on the dynamics of celestial bodies, Litohoro, Greece, July 2008 (in honor of Prof. John Hadjidemetriou)
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Degree of separability of bipartite quantum states
We investigate the problem of finding the optimal convex decomposition of a bipartite quantum state into a separable part and a positive remainder, in which the weight of the separable part is maximal.
Thiang, Guo Chuan
core +1 more source
On the quantitative estimates of the remainder in normal forms
We consider an analytic Hamiltonian system with three degrees of freedom and having a family of periodic orbits with a transition stability complex instability. We reduce the Hamiltonian to a normal form around a transition periodic orbit and we obtain H = Z^r + R^r.
Ollé Torner, Mercè +2 more
openaire +1 more source

