Results 71 to 80 of about 809,605 (268)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The normal limit distribution of the normalized number of false solutions of a one system of nonlinear random equations over the field GF(2)

Karpatsʹkì Matematičnì Publìkacìï, 2014
The theorem on a normal limit distribution of the normalized number of false solutions of a beforehand consistent system of nonlinear random equations over the field GF(2) is proved.
S.Ya. Slobodian
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Fast Exclusion Candidate Identification Based on Sparse Estimation for ARAIM Fault Exclusion Process

Remote Sensing
Advanced receiver autonomous integrity monitoring (ARAIM) is an integrity technique for a global navigation satellite system (GNSS), centered on the multiple hypothesis solution separation (MHSS) test, which assesses the consistency between a subset and ...
Hangtian Qi, Xiaowei Cui, Mingquan Lu
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Existence of normalized solutions for the nonlinear Schrödinger–Poisson–Boltzmann system

Electronic Journal of Qualitative Theory of Differential Equations
In this paper, we consider the following nonlinear Schrödinger–Poisson–Boltzmann (SPB) system under an $L^2$-norm constraint \begin{equation*} \begin{cases} -\Delta u+\lambda u+\phi u=\left|u\right|^{p-2}u&\text{in}\ \mathbb{R}^3,\\ -\Delta \phi+\kappa ...
Ruisha Chang, Kaimin Teng, Lintao Liu
doaj   +1 more source

Predicting Drag-Reducing Wall Turbulence of Surfactant Solution by Direct Numerical Simulation

Journal of Fluid Science and Technology, 2012
We performed direct numerical simulations (DNS) of turbulent channel flow of surfactant solution to investigate characteristics of modulated wall turbulence and turbulent drag reduction.
Takashi OHTA, Yuto USUI, Hiroshi YASOSHIMA   +2 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Osmotic treatment of nettle leaves in two different solutions-mass transfer kinetics [PDF]

Journal on Processing and Energy in Agriculture, 2014
The presented paper describes an investigation of osmotic treatment of nettle leaves in two different osmotic solutions (sugar beet molasses and ternary solution), under atmospheric pressure, at room temperature.
Knežević Violeta, Lončar Biljana, Nićetin Milica, Filipović Vladimir, Pezo Lato, Kuljanin Tatjana, Lević Ljubinko   +6 more
doaj  

Multiplicity results for p-Laplacian boundary value problem with jumping nonlinearities

Boundary Value Problems, 2019
We investigate the multiplicity of solutions for one-dimensional p-Laplacian Dirichlet boundary value problem with jumping nonlinearities. We obtain three theorems: The first states that there exists exactly one solution when nonlinearities cross no ...
Tacksun Jung, Q-Heung Choi
doaj   +1 more source