Results 201 to 210 of about 320,316 (300)

Normalized Caputo-Fabrizio SVIR modeling and bifurcation analysis. [PDF]

Sci Rep
Shafqat R, Al-Quran A, Alsaadi A, Djaouti AM.   +3 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Integrating Artificial intelligence within sustainable smart analytical chemistry for analyzing the divisor impact on UV-spectrophotometric efficiency of solifenacin and mirabegron combination. [PDF]

Sci Rep
Lotfy HM, Obaydo RH, Tantawy MA, Mouhamed AA.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Nanopore Fingerprinting of Neurodegenerative Proteins and Phosphoproteins within a Minute. [PDF]

JACS Au
Xin KL, Zhang LL, Li MY, Liu SC, She HQ, Ying YL, Long YT, Hu ZL.   +7 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Evidence for the existence of the <i>Magenstrasse</i> and the <i>Darmstrasse</i> when ingesting a caloric solution after a solid meal: A MRI study. [PDF]

Int J Pharm X
Großmann L, Neubauer L, Seidel ML, Kessler R, Grimm M, Weitschies W.   +5 more
europepmc   +1 more source

Normalized solutions to a quasilinear equation involving critical Sobolev exponent

In this paper we study the existence and regularity results of normalized solutions to the following quasilinear elliptic Choquard equation with critical Sobolev exponent and mixed diffusion type operators: \begin{equation*} \begin{array}{rcl} -Δ_p
Nidhi, Sreenadh, K.
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Normalized ground state of a mixed dispersion nonlinear Schrodinger equation with combined power-type nonlinearities

Electronic Journal of Differential Equations
Zhouji Ma, Xiaojun Chang, Zhaosheng Feng
doaj