Results 131 to 140 of about 229,506 (303)

On moments and tail behavior of v-stable random variables

In this paper a class of limiting probability distributions of normalized sums of a random number of i.i.d. random variables is considered. The representation of such distributions via stable laws and asymptotic behavior of their moments and tail ...
Kozubowski, Tomasz J., Panorska, Anna K.
core  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Non-homogeneous random walks with non-integrable increments and heavy-tailed random walks on strips

, 2012
We study asymptotic properties of spatially non-homogeneous random walks with non-integrable increments, including transience, almost-sure bounds, and existence and non existence of moments for first-passage and last-exit times.
MacPhee, Iain M., MacPhee, I.M., Menshikov, Mikhail V., Wade, Andrew, Ostap Hryniv, Mikhail Menshikov, Hryniv, Ostap, Wade, Andrew R., Andrew Wade, Iain MacPhee   +9 more
core   +1 more source

Characterization of active peptides derived from three leeches and comparison of their anti-thrombotic mechanisms using the tail vein thrombosis model in mice and metabonomics

Frontiers in Pharmacology
Background and aims: The increasing incidence of cardiovascular diseases has created an urgent need for safe and effective anti-thrombotic agents. Leech, as a traditional Chinese medicine, has the effect of promoting blood circulation and removing blood ...
Weichao Dong, Weichao Dong, Huajian Li, Huajian Li, Yanan Li, Yuqing Wang, Long Dai, Shaoping Wang   +7 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

On the Distortion of a Copula and its Margins

This article examines the notion of distortion of copulas, a natural extension of distortion within the univariate framework. We study three approaches to this extension: (1) distortion of the margins alone while keeping the original copula structure, (2)
Valdez, Emiliano A.
core  

Extreme values in higher-order Markov chains and decomposable graphical models [PDF]

This thesis applies the methods of conditional extremes to higher order stationary and homogeneous Markov chains, and to decomposable graphical models. These models are each defined by a set of transition kernels, together with an ordering and an initial
Casey, Adrian
core   +1 more source

Control of Percentages in Both Tails of the Normal Distribution

Technometrics, 1964
Both tolerance limits and sampling plans are discussed where percentages p/2 in each of the tails of the normal distribution are to be controlled. Tables of constants are given which have been accurately computed using the new techniques developed in the paper.
openaire   +2 more sources

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Antidepressant-like Effects of Garcinia nigrolineata Resin Extract in a Chronic Mild Stress Mouse Model: Modulation of Monoaminergic and HPA-Axis Pathways

Plants
The resin extract of Garcinia nigrolineata (GNR-E), a tropical plant used in Southeast Asian traditional medicine, was evaluated for its antidepressant-like effects in a chronic mild stress (CMS) mouse model, with imipramine as a reference drug.
Yutthana Chotritthirong, Yaowared Sumanont, Supawadee Daodee, Abdulwaris Mading, Chantana Boonyarat, Charinya Khamphukdee, Decha Kumla, Juthamart Maneenet, Kinzo Matsumoto, Anake Kijjoa, Suresh Awale, Orawan Monthakantirat   +11 more
doaj   +1 more source