Results 201 to 210 of about 82,544 (332)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Adverse pro-tumorigenic effects of IDO1 catalytic inhibitors mediated by the non-enzymatic function of IDO1 in tumor cells. [PDF]

Front Immunol
Rossini S, Ambrosino S, Volpi C, Suvieri C, Pallotta MT, Belladonna ML, Sorcini D, Macchiarulo A, Hennes E, Ziegler S, Waldmann H, Orabona C.   +11 more
europepmc   +1 more source

The impact of environmental factors on the measurement of the normalized difference vegetation index

, 2012
Attila Dobos, Róbert Víg, János Nagy
openalex   +2 more sources

Comparison Normalized Dryness Built-Up Index (NDBI) with Enhanced Built-Up and Bareness Index (EBBI) for Identification Urban in Buleleng Sub-District

, 2022
Lilis Nuraini, A Sediyo Adi Nugraha, Restu Ade Yanti, Lutfiatul Janah   +3 more
openalex   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

TRIM36 inhibits lung fibroblast activation and pulmonary fibrosis through the degradation of phospho-AKT1. [PDF]

iScience
Li Y, Yang Y, Wang Y, Shi F, Zhang Y, Wen H, Pan X, Xia C, Li Z, Cui K, Zhao G, Liu H, Wang Q, Wang L, Yu G.   +14 more
europepmc   +1 more source

Mapping Technology Space by Normalizing Technology Relatedness Networks. [PDF]

, 2015
Jeff Alstott, Giorgio Triulzi, Bowen Yan, Jianxi Luo   +3 more
openalex  

On the zeros of certain modular functions for the normalizers of congruence subgroups of low levels I [PDF]

, 2008
Junichi Shigezumi
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source