Results 141 to 150 of about 10,185 (265)

Serum Levels of miR-34a-5p, miR-30b-5p, and miR-140-5p Are Associated with Disease Activity and Brain Atrophy in Early Multiple Sclerosis. [PDF]

Int J Mol Sci
Orlandi R, Torresan L, Gobbin F, Orlandi E, Gomez Lira M, Gajofatto A.   +5 more
europepmc   +1 more source

Identification of miR-20a-5p as Robust Normalizer for Urine microRNA Studies in Renal Cell Carcinoma and a Profile of Dysregulated microRNAs. [PDF]

Int J Mol Sci, 2021
Oto J, Herranz R, Plana E, Sánchez-González JV, Pérez-Ardavín J, Hervás D, Fernández-Pardo Á, Cana F, Vera-Donoso CD, Martínez-Sarmiento M, Medina P.   +10 more
europepmc   +1 more source

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

Advanced Science, EarlyView.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He, Jing Li, Tian Guan, Yifei Ma, Zimo Zhao, Yanxia Wang, Hongjing Chen, Yingming Xu, Shuang Ge, Yexing Zhang, Yizhi Wang, Xinrui Chen, Lianghui Zhu, Yiqing Liu, Qingxia Hou, Shuyan Zhao, Xiaoqin Wang, Lili Ma, Peizhen Hu, Qiang Huang, Zihan Wang, Zhiyuan Shen, Junru Cheng, Siqi Zeng, Jiurun Chen, Zhen Song, Chao He, Zhe Wang, Yonghong He   +28 more
wiley   +1 more source

Bioluminescence-Driven Optimization of Geminivirus-Based Vectors as Tools for Plant Biotechnology. [PDF]

ACS Synth Biol
Garcia-Perez E, Vazquez-Vilriales V, Vazquez-Vilar M, Castillo AG, Sarkisyan KS, Lozano-Duran R, Bejarano ER, Orzaez D.   +7 more
europepmc   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Fundamental motifs and parity within the crystallographic point groups. [PDF]

J Appl Crystallogr
Julian MM, Macauley M.
europepmc   +1 more source

Normal Subgroups of Monomial Groups [PDF]

Proceedings of the American Mathematical Society, 1957
Crouch, R. B., Scott, W. R.
openaire   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Comparison of multi-miRNA models from donor-matched plasma and cerebrospinal fluid as candidate biomarkers for Alzheimer's disease prediction. [PDF]

Sci Rep
Sandau US, Wiedrick JT, McFarland TJ, Chen S, Quinn JF, Saugstad JA.   +5 more
europepmc   +1 more source

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

Advanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen, Dingru Li, Yingna Liao, Zehua Wang, Chunbin Zhu, Zifeng Zhang, Liquan Jin, Yueyue Chen, Jiaoshun Chen, Junyi Xu, Miaoyan Wei, Rong Tang, Xianjun Yu, Si Shi   +13 more
wiley   +1 more source