One‐Year Effectiveness of Upadacitinib in Perianal Crohn's Disease: A Real‐World GETAID Study
In a real‐world cohort of patients with highly refractory perianal Crohn's disease, upadacitinib induced clinical remission at 12 months in 26% of patients with fistulizing disease and 25% of those with isolated anal ulcerations. ABSTRACT Introduction Upadacitinib (UPA) is effective for treating luminal Crohn's disease (CD), but data on perianal CD ...
Nicolas Richard +13 more
wiley +1 more source
Sustainability in Healthcare: The Role of Digital Technologies for Improving Patient Engagement
ABSTRACT Sustainability in healthcare is getting considerable research attention as systems worldwide tend to balance environmental, social, and economic factors. In this context, digital technologies have demonstrated significant potential to enhance engagement among different consumer groups across various industries.
Francesco Schiavone +4 more
wiley +1 more source
Ripple Effects: Social Turmoil Following Infant Kidnapping Attempts in Wild Geladas
Graphical abstract illustrating the social consequences of infant kidnapping in wild geladas (Theropithecus gelada). The study monitors a 28‐day period divided into a 14‐day pre‐kidnapping phase and a 14‐day post‐kidnapping phase. ABSTRACT Infant kidnapping is an extreme social disruption reported in some primate species, yet its consequences on social
Alice Galotti +13 more
wiley +1 more source
Cerebral air embolism after implantation of a leadless pacemaker via the right internal jugular vein: a case report. [PDF]
Ollitrault P +4 more
europepmc +1 more source
European S2k guidelines on management of autoimmune blistering diseases in children and adolescents
Autoimmune blistering disorders (AIBDs) in children are rare, challenging to diagnose and treat and often require immunosuppressants. Until now, no paediatric care guidelines existed. The EADV Task Force for AIBDs has developed the consensus‐based recommendations, enabling physicians to adopt a uniform, tailored treatment strategy to improve outcomes ...
A. Nanda +31 more
wiley +1 more source
Identification of immunomodulators associated with atrial fibrillation reporting to better understand AF immunologic mechanisms: a Vigibase retrospective disproportionality analysis and a literature review. [PDF]
Font J +11 more
europepmc +1 more source
Political and Institutional Development in England
ABSTRACT This paper revisits the political and institutional development of England from the Magna Carta to the Glorious Revolution. I argue that institutional change in this period is best understood through the lens of coalition formation. Political elites had heterogeneous preferences over first two, and then three, recurring axes of disagreement ...
Mark Koyama
wiley +1 more source
The Chalk Streams of Southern England and Northern France Harbour Substantial Unique Components of the Overall Genetic Diversity of Atlantic Salmon (<i>Salmo salar</i> L.). [PDF]
King RA, Evanno G, Stevens JR.
europepmc +1 more source
Chiral tri‐ and pentahydroxy spirocyclopentane‐indolizidines were synthesized using lithium diisopropylamide “LDA” promoted diallylation and tetrahydrofuran “THF” ring‐opening in a one‐pot procedure as a key step. The sequence leading to the targeted hydroxy‐spiroindolizidines was achieved by cis‐dihydroxylation followed by reduction of the enamine and
Paula Fraňová +6 more
wiley +1 more source
Editorial-A Milestone in the Technological Development of Hadrontherapy, in FranceHadrontherapy, cryogenic cyclotron. [PDF]
Habrand JL +4 more
europepmc +1 more source

