Early Autonomic Burden in Prodromal Parkinson's Disease Predicts Cognitive Impairment
Abstract Background Autonomic dysfunction is a known contributor to cognitive impairment in Parkinson's disease (PD), but its impact during prodromal stage is unknown. Objective The aim was to determine whether early autonomic burden predicts incident cognitive impairment in prodromal PD.
A. Enrique Martinez‐Nunez +5 more
wiley +1 more source
Mendelian randomization study of maternal coffee consumption and its influence on birthweight, stillbirth, miscarriage, gestational age and pre-term birth. [PDF]
Brito Nunes C +11 more
europepmc +1 more source
Perspective: Depression in Persons with Parkinson's Disease
Abstract Depression is a prevalent and disabling syndrome characterized by sustained sadness and/or anhedonia, as well as cognitive and physical symptoms. In Parkinson's disease (PD), depression is both common and clinically challenging due to overlapping symptoms and complex etiologic interactions. Major depressive disorder occurs in approximately 17%
Albert F.G. Leentjens +1 more
wiley +1 more source
Digging into the admixture strata of current-day Canary Islanders based on mitogenomes. [PDF]
García-Olivares V +11 more
europepmc +1 more source
A Severity‐Agnostic Atrophy Pattern in Spinocerebellar Ataxia Type 3: Volumetrics from ENIGMA‐Ataxia
Background Spinocerebellar ataxia type 3 (SCA3) is a rare, inherited neurodegenerative disease characterized by progressive loss of motor coordination. Objectives We undertook a multisite magnetic resonance imaging study to profile the spatial spread of atrophy across the brain, determine whether atrophy preferentially maps onto specific functional ...
Jason W. Robertson +43 more
wiley +1 more source
A Bayesian multi-proxy contribution to the socioeconomic, political, and cultural history of late medieval Capitanata (southern Italy). [PDF]
Cocozza C +11 more
europepmc +1 more source
Hölder Regularity of the Solutions of Fredholm Integral Equations on Upper Ahlfors Regular Sets
ABSTRACT We extend to the context of metric measured spaces, with a measure that satisfies upper Ahlfors growth conditions, the validity of (generalized) Hölder continuity results for the solution of a Fredholm integral equation of the second kind. Here we note that upper Ahlfors growth conditions include also cases of nondoubling measures.
Massimo Lanza de Cristoforis +1 more
wiley +1 more source
Autoimmune Hepatitis in a Patient With Common Variable Immunodeficiency. [PDF]
Myneedu K +5 more
europepmc +1 more source
Animator Norman McLaren is best known for his experimental films using pioneering techniques and his work as founder of the animation department of the National Film Board of Canada (NFB), but little mention is made of his Scottish heritage or his personal life.
openaire +2 more sources
ABSTRACT Introduction Weight loss in people with amyotrophic lateral sclerosis (pwALS) is a poor prognostic factor. We aimed to develop an intervention to support pwALS to increase calorie intake and explore feasibility and acceptability. Methods Intervention development was underpinned by the Capability, Opportunity and Motivation (COM‐B) model and ...
Alys Wyn Griffiths +24 more
wiley +1 more source

