Chronic respiratory symptoms and airway responsiveness to methacholine are associated with eosinophilia in older men: the Normative Aging Study [PDF]
JT Annema+6 more
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In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang+10 more
wiley +1 more source
Dissociable encoding of evolving beliefs and momentary belief updates in distinct neural decision signals. [PDF]
Parés-Pujolràs E, Kelly SP, Murphy PR.
europepmc +1 more source
Normative Grundstrukturen der Behandlung nichttarifärer Handelshemmnisse in der WTO/GATT-Rechtsordnung. Eine Untersuchung unter besonderer Berücksichtigung des Countertrade [PDF]
Christian Tietje
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Nanoscale Curvature Regulates YAP/TAZ Nuclear Localization Through Nuclear Deformation and Rupture
This study uses experiments and biophysical modeling to examine the response and adaptation of cells to nanoscale topography of surfaces. It is shown that cytoskeletal assembly and nuclear localization of transcription regulatory factors such as yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (TAZ) can be tuned by ...
Emmet A. Francis+7 more
wiley +1 more source
Characterizing the heterogeneity of neurodegenerative diseases through EEG normative modeling. [PDF]
Tabbal J+12 more
europepmc +1 more source
Estimation and Inference for Normative Inequality Indices [PDF]
Ian Rongve, Charles M. Beach
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Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li+11 more
wiley +1 more source
Vermicular Eutectic Multi‐Principal Element Alloy with Exceptional Strength and Ductility
Eutectic multi‐principal element alloys (EMPEAs) typically exhibit rod‐like or lamellar microstructures, constraining further mechanical improvements. This study introduces a novel (AlCrFe2)65Ni35 EMPEA with a unique vermicular microstructure, achieving unprecedented strength‐ductility synergy.
Liufei Huang+11 more
wiley +1 more source