Results 151 to 160 of about 1,400,848 (384)
Advanced Science, EarlyView.This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang +10 more
wiley +1 more source
Moral Facts, Possible Moral Worlds and Naturalized Ethics [PDF]
, 2008 Given his commitment to the project of naturalizing every normative aspect of philosophy; reducing its a priori content to some sort of empirical enterprise, Quine’s inroad into moral philosophy is expected to set the stage for the project of ...
Gbenga, Fasiku
core +1 more source
Advanced Science, EarlyView.Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He +18 more
wiley +1 more source
THE EVOLUTION OF LAW PRINCIPLES IN A MODERN STATE
Russian Journal of Economics and Law, 2007 The article views the issues of changing and developing of the law principles, their increasing impact on the legal system. The author proves the necessity to attribute new content to the law principles under the influence of normative ethics of the ...
M. V. Baiteyeva
doaj
Transformative medical ethics: A framework for changing practice according to normative–ethical requirements [PDF]
, 2023 Katja Kuehlmeyer +3 more
openalex +1 more source
Ethical Precision in Nanoscale Brain Interfacing
Advanced Science, EarlyView.As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley +1 more source
CORPORATE ETHICAL IDENTITY AS DETERMINANT OF FIRM PERFORMANCE: A TEST OF THE MEDIATING ROLE OF STAKEHOLDER SATISFACTION [PDF]
In this article, we empirically assess the impact of the Corporate Ethical Identity (CEI) on the firm’s financial performance. Drawing on formulation of both normative and instrumental stakeholder theory, we argue that firms with a strong ethical ...
Jordi Surroca +2 more
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Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound
Advanced Science, EarlyView.Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García +11 more
wiley +1 more source
Ban Glyphosate—Does It Affect the Swedish Farmers' Willingness to Grow Cover Crops?
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT The cultivation of cover crops is one of the new Eco‐scheme practices introduced in Sweden. This study examines how the design of policy attributes of these schemes influences farmers' willingness to grow cover crops on arable land, with particular focus on the potential impact of a glyphosate ban.
Vivian Wei Huang +2 more
wiley +1 more source
The Alienation Objection to Consequentialism [PDF]
, 2020 An ethical theory is alienating if accepting the theory inhibits the agent from fitting participation in some normative ideal, such as some ideal of integrity, friendship, or community.
Baker, Calvin, Maguire, Barry
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