Results 101 to 110 of about 20,049 (292)

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

EFFICIENCY OF THE INSTITUTION OF INDEPENDENT ANTI-CORRUPTION EXPERTISE OF NORMATIVE LEGAL ACTS AND THEIR DRAFTS

, 2015
Objective: to determine the factors affecting the efficiency of civil society representatives accredited by the Russian Ministry of Justice as independent experts authorized to conduct anti-corruption expertise of normative legal acts and their drafts ...
R. O. Dolotov
core   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

British Journal of Clinical Pharmacology, EarlyView.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber, Sophie‐Charlotte Bartel, Michael Boch, Christoph Rosen, Michael Bodmer, Balthasar Luzius Hug, Thomas Stammschulte, Patrick E. Beeler   +7 more
wiley   +1 more source

The United States: A normative power? CEPS Working Document No. 291/May 2008. [PDF]

, 2008
To what degree may the US be considered a normative power? The US foreign policy mainstream tends to reflect a varying blend of normative and hegemonic approaches.
Hamilton, Daniel S.
core  

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Tłumaczenie tekstów aktów prawnych w kontekście ich wielopoziomowości

Między Oryginałem a Przekładem
TRANSLATION OF LEGAL ACTS IN THE CONTEXT OF THEIR MULTI-LEVEL NATURE The main aim of the article is to discuss the problem of translating legal texts from the perspective of their multi-level nature.
Kamil Dąbrowski
doaj   +1 more source

Problems of modeling further development of civil legislation of the Russian Federation

MATEC Web of Conferences, 2018
The article provides of civil modeling of civil legislation development, shows its significance and peculiarities, structural elements, gives their characteristics, concludes the necessity of an integrated approach to Problem of civil models.
Semyakin Mikhail, Dobrynina Larisa, Gubareva Anna, Gudovicheva Lubov   +3 more
doaj   +1 more source

THE METHODOLOGICAL PRINCIPLES OF NORMATIVE LEGAL ACTS MONITORING

Visnyk of the Lviv University. Series Law, 2016
Managed to achieve minor results in the development of the conceptual and methodological framework, and the implementation of legal monitoring in the mechanism of making and implementing laws. This process stimulates the development of a new direction in legal science, which is designed to provide practice necessary knowledge and recommendations on ...
openaire   +2 more sources

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source