Global prevalence of asymptomatic norovirus infection in outbreaks: a systematic review and meta-analysis [PDF]
Background Although many studies on asymptomatic norovirus infection in outbreaks have been conducted globally, structured data (important for emergency management of outbreaks) on the prevalence of this epidemic are still not available.
Jun Wang+4 more
doaj +3 more sources
Unraveling the interplay between norovirus infection, gut microbiota, and novel antiviral approaches: a comprehensive review [PDF]
Norovirus infection is a leading cause of acute gastroenteritis worldwide and can also cause harmful chronic infections in individuals with weakened immune systems.
Geng-Hao Bai+8 more
doaj +3 more sources
Bacterial extracellular vesicles control murine norovirus infection through modulation of antiviral immune responses [PDF]
Human norovirus is the primary cause of non-bacterial gastroenteritis globally and is the second leading cause of diarrheal deaths in children in developing countries. However, effective therapeutics which prevent or clear norovirus infection are not yet
Sutonuka Bhar+7 more
doaj +3 more sources
Prevalence and Etiological Characteristics of Norovirus Infection in China: A Systematic Review and Meta-Analysis [PDF]
Norovirus is a common cause of sporadic cases and outbreaks of gastroenteritis worldwide, although its prevalence and the dominant genotypes responsible for gastroenteritis outbreaks remain obscure.
Ting-Ting Li+10 more
doaj +3 more sources
Lactobacilli as a Vector for Delivery of Nanobodies against Norovirus Infection. [PDF]
Passive administration of neutralizing antibodies (Abs) is an attractive strategy for the control of gastrointestinal infections. However, an unanswered practical concern is the need to assure the stability of sufficient amounts of orally administered ...
Yuki Y+8 more
europepmc +2 more sources
Norovirus Gastroenteritis in a Birth Cohort in Southern India. [PDF]
BACKGROUND:Noroviruses are an important cause of gastroenteritis but little is known about disease and re-infection rates in community settings in Asia. METHODS:Disease, re-infection rates, strain prevalence and genetic susceptibility to noroviruses were
Vipin Kumar Menon+13 more
doaj +5 more sources
Clinical and In Vitro Evidence Favoring Immunoglobulin Treatment of a Chronic Norovirus Infection in a Patient With Common Variable Immunodeficiency. [PDF]
Background Immunocompromised individuals can become chronically infected with norovirus, but effective antiviral therapies are not yet available. Methods Treatments with nitazoxanide, ribavirin, interferon alpha-2a, and nasoduodenally administered ...
van Kampen JJA+10 more
europepmc +2 more sources
Development of a rapid and accurate CRISPR/Cas13-based diagnostic test for GII.4 norovirus infection. [PDF]
Genogroup II genotype 4 (GII.4) norovirus causes acute gastroenteritis in children, and its infection is more severe than that of other genotypes. Early and precise detection and treatment are critical for controlling its spread and reducing the severity
Duan L+10 more
europepmc +2 more sources
Unsuccessful treatment of chronic norovirus infection with enteral immunoglobulin in patients with common variable immunodeficiency, case report [PDF]
Background: Norovirus gastroenteritis is commonly an acute infection that lasts 2–3 days, but in immunocompromised patients norovirus can cause a chronic gastroenteritis lasting for years.
A.C.W. Christensen+4 more
doaj +2 more sources
Long Term Norovirus Infection in a Patient with Severe Common Variable Immunodeficiency [PDF]
Norovirus is the most common cause of acute non-bacterial gastroenteritis. Immunocompromised patients can become chronically infected, with or without symptoms. In Europe, common variable immunodeficiency (CVID) is one of the most common inborn errors of
Loa Ottosson+9 more
doaj +2 more sources