Results 111 to 120 of about 3,289,695 (270)
Beyond Pathology: α‐Synuclein Homeostasis and Three Principles to Guide Research
Movement Disorders Clinical Practice, EarlyView.
Alberto J. Espay, Andrew J. Lees
wiley +1 more source
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen +5 more
wiley +1 more source
Background Swimming in fecally-contaminated waterbodies can result in gastrointestinal infections. However, the pathogenic microorganisms responsible are not well understood because sporadic cases of illness are not reported completely, exposure ...
T. Wade +8 more
semanticscholar +1 more source
Timeline of events ABSTRACT Moderate‐to‐severe ulcerative colitis can be effectively treated with JAK‐1 inhibition, but platelet counts should be closely monitored, especially in active disease. We confirmed immune‐mediated thrombocytopenia (ITP) in one of our patients after the initiation of filgotinib. Whether this was drug‐induced is uncertain.
M. J. van der Hoff +2 more
wiley +1 more source
A spoonful of sugar: the application of glycopolymers in therapeutics [PDF]
Glycopolymers, synthetic polymers displaying carbohydrate moieties, have been linked to many potential applications at the biology–chemistry interface. One area that holds particular promise is the employment of glycopolymers as vehicles for therapeutics
Cameron, Neil R., Spain, Sebastian G.
core +2 more sources
ABSTRACT Background Fecal microbiota transplantation (FMT) has emerged as a groundbreaking strategy for modulating the gut microbiome and improving cancer treatment outcomes. This review synthesizes the current evidence on the role of FMT in oncology, focusing on its potential to enhance the efficacy of immunotherapy, restore microbiome homeostasis ...
Aswathi Ramesh +3 more
wiley +1 more source
Viruses in nondisinfected drinking water from municipal wells and community incidence of acute gastrointestinal illness. [PDF]
BackgroundGroundwater supplies for drinking water are frequently contaminated with low levels of human enteric virus genomes, yet evidence for waterborne disease transmission is lacking.ObjectivesWe related quantitative polymerase chain reaction (qPCR ...
Borchardt, Mark A +4 more
core
Estimating the Hospital Burden of Norovirus-Associated Gastroenteritis in England and Its Opportunity Costs for Nonadmitted Patients. [PDF]
Background: Norovirus places a substantial burden on healthcare systems, arising from infected patients, disease outbreaks, beds kept unoccupied for infection control, and staff absences due to infection.
Adams, Natalie +11 more
core +2 more sources
Urgent attention to global food safety in catering is necessary to address hygiene, training, and tech‐based strategies to counter foodborne diseases. ABSTRACT Food safety in the catering sector is an essential public health issue, as foodborne diseases (FBDs) continue to pose significant threats worldwide.
Anwar Ali +7 more
wiley +1 more source
Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence. [PDF]
Interactions of host cell factors with RNA sequences and structures in the genomes of positive-strand RNA viruses play various roles in the life cycles of these viruses.
Bailey, Dalan +10 more
core +4 more sources

