Results 141 to 150 of about 3,213,792 (286)

Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

eLife, 2019
Knowledge of the host factors required for norovirus replication has been hindered by the challenges associated with culturing human noroviruses. We have combined proteomic analysis of the viral translation and replication complexes with a CRISPR screen,
Myra Hosmillo, Jia Lu, Michael R McAllaster, James B Eaglesham, Xinjie Wang, Edward Emmott, Patricia Domingues, Yasmin Chaudhry, Tim J Fitzmaurice, Matthew KH Tung, Marc Dominik Panas, Gerald McInerney, Nicolas Locker, Craig B Wilen, Ian G Goodfellow   +14 more
doaj   +1 more source

Prospective cohort study to investigate the burden and transmission of acute gastroenteritis in care homes: a study protocol. [PDF]

, 2017
INTRODUCTION: Noroviruses are the leading cause of acute gastroenteritis in all age groups, but illness is more severe and causes excess mortality in the elderly, particularly those in long-term care.
Allen, David J, Beeching, Nicholas J, Harris, John P, Inns, Thomas, Iturriza-Gomara, Miren, O'Brien, Sarah J, Pulawska-Czub, Anna, Read, Jonathan M, Vivancos, Roberto   +8 more
core   +3 more sources

Wandering Spleen in a Pediatric Lung Transplant Patient With Filamin A Deficiency: An Incidental Finding

Pediatric Transplantation, Volume 29, Issue 6, September 2025.
ABSTRACT Background Filamin A (FLNA) deficiency is a known cause of progressive lung disease and need for pediatric lung transplant; however, what may be less well known to lung transplant providers are the extrapulmonary complications of FLNA deficiencies, such as wandering spleen.
Savannah Ellis Knight, Mayel Yepez Donado, Maria Carolina Gazzaneo   +2 more
wiley   +1 more source

Prophylactic efficacy of orally administered Bacillus poly-γ-glutamic acid, a non-LPS TLR4 ligand, against norovirus infection in mice

Scientific Reports, 2018
Poly-gamma-glutamic acid (γ-PGA), an extracellular biopolymer produced by Bacillus sp., is a non-canonical toll-like receptor 4 (TLR4) agonist. Here we show its antiviral efficacy against noroviruses.
Wooseong Lee, Minwoo Kim, Seung-Hoon Lee, H. Jung, Jong-Won Oh   +4 more
semanticscholar   +1 more source

Functional analysis of RNA structures present at the 3' extremity of the murine norovirus genome: the variable polypyrimidine tract plays a role in viral virulence. [PDF]

, 2010
Interactions of host cell factors with RNA sequences and structures in the genomes of positive-strand RNA viruses play various roles in the life cycles of these viruses.
Bailey, Dalan, Benson, Alicia, Chung, Liliane Man Wah, Goodfellow, Ian, Karakasiliotis, Ioannis, McFadden, Nora, Rees, Jivan, Reese, Jivan, Simmonds, Peter, Vashist, Surender, Yarovinsky, Felix   +10 more
core   +3 more sources

Urban political ecologies of sewage surveillance: Creating vital and valuable public health data from wastewater

Transactions of the Institute of British Geographers, Volume 50, Issue 3, September 2025.
Abstract With the outbreak of COVID‐19, wastewater surveillance for public health rapidly emerged and expanded globally. In this article we chart the variegated ecosystem of private firms that work closely with public and non‐profit entities to transform metabolic flows of sewage into vital and valuable bioinformation, thereby creating new multi ...
Mohammed Rafi Arefin, Carolyn Prouse
wiley   +1 more source

Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases

Journal of Analytical Science and Technology
The human norovirus (abbreviated as HuNV) is the most common agent responsible for acute viral gastroenteritis. Despite being recognized as a water-borne pathogenic virus for a long time, the cellular tropism of norovirus has not yet been clearly ...
Sung Ho Yun, Md Arif-Ur Rahman, Soo-Bin Nam, Soo Hyeon Kim, Gyuri Kim, Kun Cho, Jong-Soon Choi   +6 more
doaj   +1 more source

Norovirus Surveillance among Callers to Foodborne Illness Complaint Hotline, Minnesota, USA, 2011–2013

Emerging Infectious Diseases, 2013
Norovirus is the leading cause of foodborne disease in the United States. During October 2011–January 2013, we conducted surveillance for norovirus infection in Minnesota among callers to a complaint-based foodborne illness hotline who reported diarrhea ...
Amy A. Saupe, Dawn Kaehler, Elizabeth A. Cebelinski, Brian Nefzger, Aron J. Hall, Kirk E. Smith   +5 more
doaj   +1 more source

Minimally Invasive Saliva Testing to Monitor Norovirus Infection in Community Settings

Journal of Infectious Diseases, 2018
Background Norovirus is a leading cause of acute gastroenteritis worldwide. Routine norovirus diagnosis requires stool collection. The goal of this study was to develop and validate a noninvasive method to diagnose norovirus to complement stool ...
N. Pisanic, Sarah-Blythe Ballard, Fabiola D Colquechagua, Ruthly François, N. Exum, P. Yori, K. Schwab, D. Granger, B. Detrick, M. Olortegui, H. Mayta, G. Sanchez, R. Gilman, C. Heaney, J. Vinjé, M. Kosek   +15 more
semanticscholar   +1 more source

A comprehensive functional map of the hepatitis C virus genome provides a resource for probing viral proteins. [PDF]

, 2014
UnlabelledPairing high-throughput sequencing technologies with high-throughput mutagenesis enables genome-wide investigations of pathogenic organisms. Knowledge of the specific functions of protein domains encoded by the genome of the hepatitis C virus ...
Arumugaswami, Vaithilingaraja, Chen, Shu-Hwa, Chen, Zugen, Chu, Virginia, Lin, Chung-Yen, Lo, Hung-Hao, Olson, C Anders, Qi, Hangfei, Remenyi, Roland, Stokelman, Tamar, Su, Sheng-Yao, Sun, Ren, Truong, Shawna, Wu, Nicholas C, Wu, Ting-Ting   +14 more
core   +2 more sources