Results 21 to 30 of about 3,213,792 (286)

Glycan Recognition in Human Norovirus Infections [PDF]

Viruses, 2021
Recognition of cell-surface glycans is an important step in the attachment of several viruses to susceptible host cells. The molecular basis of glycan interactions and their functional consequences are well studied for human norovirus (HuNoV), an important gastrointestinal pathogen.
Victoria R. Tenge, Liya Hu, B. V. Venkataram Prasad, Göran Larson, Robert L. Atmar, Mary K. Estes, Sasirekha Ramani   +6 more
openaire   +4 more sources

Infection control for norovirus [PDF]

Clinical Microbiology and Infection, 2014
Norovirus infections are notoriously difficult to prevent and control, owing to their low infectious dose, high shedding titre, and environmental stability. The virus can spread through multiple transmission routes, of which person-to-person and foodborne are the most important.
Geun Woo Park, Aron J. Hall, Jan Vinjé, Umesh D. Parashar, Everardo Vega, Leslie Barclay, Ben Lopman   +6 more
openaire   +3 more sources

CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection

Nature Communications, 2023
Culture methods for studying human norovirus infection have been recently established. Here, Ayyar and colleagues use human intestinal enteroids to dissect viral entry mechanisms and show that CLIC-mediated endocytosis and wound repair pathways are ...
B. Ayyar, K. Ettayebi, W. Salmen, Umesh C. Karandikar, F. Neill, Victoria R. Tenge, S. Crawford, E. Bieberich, B. Prasad, R. Atmar, M. Estes   +10 more
semanticscholar   +1 more source

Norovirus Infection in Harbor Porpoises [PDF]

Emerging Infectious Diseases, 2017
A norovirus was detected in harbor porpoises, a previously unknown host for norovirus. This norovirus had low similarity to any known norovirus. Viral RNA was detected primarily in intestinal tissue, and specific serum antibodies were detected in 8 (24%) of 34 harbor porpoises from the North Sea.
de Graaf, Miranda, Bodewes, Rogier, van Elk, Cornelis E., van de Bildt, Marco, Getu, Sarah, Aron, Georgina I., Verjans, Georges M.G.M., Osterhaus, Albert D.M.E., van den Brand, Judith M.A., Kuiken, Thijs, Koopmans, Marion P.G.   +10 more
openaire   +5 more sources

TLR7 Agonists Display Potent Antiviral Effects against Norovirus Infection via Innate Stimulation [PDF]

Antimicrobial Agents and Chemotherapy, 2018
Daniel Enosi Tuipulotu, Natalie E. Netzler, Jennifer H. Lun, Jason M. Mackenzie, Peter A. White   +4 more
openalex   +2 more sources

Infection of neonatal mice with the murine norovirus strain WU23 is a robust model to study norovirus pathogenesis

Lab animal, 2023
A mouse model to study norovirus pathogenesis is described. The murine norovirus strain WU23, originally isolated from an intestinal site, induces severe but self-resolving diarrhea in neonates, reflecting the pathology observed during human norovirus ...
Amy Peiper, Emily W. Helm, Quyen Nguyen, M. Phillips, Caroline G. Williams, Dhairya Shah, Sarah M. Tatum, Neha Iyer, M. Grodzki, Laura B. Eurell, A. Nasir, Megan T. Baldridge, Stephanie M. Karst   +12 more
semanticscholar   +1 more source

Actualités sur les norovirus [PDF]

médecine/sciences, 2010
Noroviruses belong to the Caliciviridae family. They are a major cause of sporadic cases and outbreaks of gastroenteritis in all age groups, and are responsible for a considerable disease burden in industrialized countries. Noroviruses are single-stranded RNA viruses, and show great genetic diversity making their detection difficult. Noroviruses can be
de Rougemont, Alexis, Ambert-Balay, Katia, Belliot, Gaël, Pothier, Pierre   +3 more
openaire   +4 more sources

Secretor status strongly influences the incidence of symptomatic norovirus infection in a genotype-dependent manner in a Nicaraguan birth cohort.

Journal of Infectious Diseases, 2021
BACKGROUND The role of histo-blood group on the burden and severity of norovirus gastroenteritis in young infants has not been well documented. METHODS Norovirus gastroenteritis was assessed in 443 Nicaraguan children followed from birth until 3 years ...
Yaoska Reyes, F. González, Lester Gutiérrez, Patricia Blandón, Edwing Centeno, Omar Zepeda, Christian Toval-Ruíz, L. Lindesmith, R. Baric, N. Vielot, M. Diez-Valcarce, J. Vinjé, L. Svensson, S. Becker-Dreps, J. Nordgren, F. Bucardo   +15 more
semanticscholar   +1 more source

CS8-01 Norovirus Infection: An Emerging Enteric Infection

International Journal of Infectious Diseases, 2009
Joseph J.�Y. Sung
openalex   +3 more sources

Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

mBio, 2020
Several studies have demonstrated that secretor status is associated with susceptibility to human norovirus (HuNoV) infection; however, previous reports found that FUT2 expression is not sufficient to allow infection with HuNoV in a variety of continuous
K. Haga, K. Ettayebi, Victoria R. Tenge, Umesh C. Karandikar, Miranda A. Lewis, Shih-Ching Lin, F. Neill, B. Ayyar, Xi-Lei Zeng, G. Larson, S. Ramani, R. Atmar, Mary K. Estes   +12 more
semanticscholar   +1 more source