Results 41 to 50 of about 3,213,792 (286)
Expression of Ifnlr1 on intestinal epithelial cells is critical to the antiviral effects of IFN-lambda against norovirus and reovirus [PDF]
, 2017 Lambda interferon (IFN-λ) has potent antiviral effects against multiple enteric viral pathogens, including norovirus and rotavirus, in both preventing and curing infection. Because the intestine includes a diverse array of cell types, however, the cell(s)
Baldridge, Megan T +7 more
core +2 more sources
Journal of Microbiology, Immunology and Infection, 2021 Objectives: Norovirus is associated with one-fifth of all gastroenteritis cases, but basic epidemiological data is lacking, especially in developing countries.
Ran-Ran Cao +11 more
doaj +1 more source
Norovirus infection in primary immune deficiency [PDF]
Reviews in Medical Virology, 2017 SummaryNorovirus is acknowledged to be a leading cause of acute gastroenteritis worldwide, and its importance as a cause of chronic infection in immune deficient hosts is increasingly recognised. Current evidence suggests that a coordinated response of innate immune mechanisms, CD8+ cytotoxicity and a humoral response, with CD4+ orchestration, is ...
Li-An K Brown +4 more
semanticscholar +4 more sources
New proof-of-concept in viral inactivation: virucidal efficacy of 405 nm light against feline calicivirus as a model for norovirus decontamination [PDF]
, 2016 The requirement for novel decontamination technologies for use in hospitals is ever present. One such system uses 405 nm visible light to inactivate microorganisms via ROS-generated oxidative damage.
Anderson, John G. +7 more
core +1 more source
Norovirus infection in immunocompromised hosts [PDF]
Clinical Microbiology and Infection, 2014 Acute gastroenteritis caused by noroviruses often has a duration of 2-3 days and is characteristically self-limiting. In contrast, chronic infection caused by noroviruses in immunocompromised individuals can last from weeks to years, making clinical management difficult.
openaire +3 more sources
Human Norovirus: Experimental Models of Infection [PDF]
Viruses, 2019 Human noroviruses (HuNoVs) are a leading cause of acute gastroenteritis worldwide. HuNoV infections lead to substantial societal and economic burdens. There are currently no licensed vaccines or therapeutics for the prevention or treatment of HuNoVs. A lack of well-characterized in vitro and in vivo infection models has limited the development of HuNoV
Kyle V. Todd, Ralph A. Tripp
openaire +3 more sources
Norovirus Infection and Disease in an Ecuadorian Birth Cohort: Association of Certain Norovirus Genotypes With Host FUT2 Secretor Status. [PDF]
, 2015 BACKGROUND: Although norovirus is the most common cause of gastroenteritis, there are few data on the community incidence of infection/disease or the patterns of acquired immunity or innate resistance to norovirus.
Broncano, N +12 more
core +1 more source
Norovirus Infectivity in Humans and Persistence in Water [PDF]
Applied and Environmental Microbiology, 2011 ABSTRACTTo examine the long-term infectivity of human norovirus in water, 13 study subjects were challenged at different time points with groundwater spiked with the prototype human norovirus, Norwalk virus. Norwalk virus spiked in groundwater remained infectious after storage at room temperature in the dark for 61 days (the last time point tested ...
Melissa Dowd +11 more
openaire +3 more sources
BMC Public Health, 2020 Introduction A leading cause of acute gastroenteritis, norovirus can be transmitted by infected food handlers but norovirus outbreaks are not routinely investigated in Kenya. We estimated norovirus prevalence and associated factors among food handlers in
Eliud Wainaina +4 more
doaj +1 more source
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]
, 2017 Vesivirus 2117 is an adventitious agent that in 2009, was identified as a contaminant of CHO cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme.
Bhella, David +8 more
core +1 more source