Results 11 to 20 of about 1,488,469 (300)

The relationship between teachers’ professional wellbeing and principals’ leadership styles

open access: yesPerspectives in Education, 2020
Challenges and changes in the South African education system could have an impact on teachers’ professional wellbeing, which, in turn, results in changes in teacher retention rates.
Cornelius Petrus Van der Vyver   +2 more
doaj   +3 more sources

Crime and Social media [PDF]

open access: yes, 2019
Purpose-The study complements the scant macroeconomic literature on the development outcomes of social media by examining the relationship between Facebook penetration and violent crime levels in a cross-section of 148 countries for the year 2012 ...
Asongu, Simplice   +3 more
core   +3 more sources

A Pragmatic Analysis of President Nnamdi Azikiwe’s Speech: a response to the foremost Military Seizure of Power in Nigeria – January, 1966 [PDF]

open access: yesJournal of Studies in Social Sciences and Humanities, 2021
This study is a pragmatic analysis of President Nnamdi Azikiwe’s speech responding to the foremost Military Seizure of Power in Nigeria – January, 1966.
Emmanuel Tobi Adegoriolu, E-mail: tobiadegoriolu@gmail.com   +4 more
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Yemaya, No. 26, November 2007 [PDF]

open access: yes, 2007
Asia/ India - Restricting Lives and Livelihoods. North America/ Mexico - Empowering Agenda?. Africa/ South Africa - Aren’t We Missing Something?. Africa/ Zanzibar - Winning Strategies.

core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Returnees in the Maghreb. A European perspective. Egmont Security Policy Brief No. 120 December 2019 [PDF]

open access: yes, 2019
More than 10,000 individuals travelled from Europe and North Africa to fight in Syria and Iraq. Now, Europe and North Africa are dealing with the challenge of returning foreign fighters, mostly separately.
Renard, Thomas
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

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