Results 111 to 120 of about 363,904 (309)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Application of General Circulation Models to Assess the Potential Impact of Climate Change on Potential Distribution and Relative Abundance of Melanoplus sanguinipes (Fabricius) (Orthoptera: Acrididae) in North America

open access: yesPsyche: A Journal of Entomology, 2011
Climate is the dominant factor determining the distribution and abundance of most insect species. In recent years, the issue of climatic changes caused by human activities and the effects on agriculture has raised concern.
O. Olfert, R. M. Weiss, D. Kriticos
doaj   +1 more source

Evolution of Forensic Linguistics Publication: From a Europe and North America Continent (1980 – 2021)

open access: yes, 2023
{"references": ["Ariani, M. G., Sajedi, F., & Sajedi, M. (2014). Forensic Linguistics: A Brief Overview of the Key Elements. Procedia - Social and Behavioral Sciences, 158, 222\u2013225. https://doi.org/10.1016/j.sbspro.2014.12.078", "Coulthard, M., & Johnson, A. (2007). An Introduction to Forensic Linguistics: Language in Evidence.
openaire   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Advanced Solid-State Array Spectrometer (ASAS) data sets from the 1990 field season: A unique look at two forested ecosystems [PDF]

open access: yes
The Advanced Solid-state Array Spectrometer (ASAS) is a pointable imaging spectrometer which uses a solid-state array to acquire imagery of terrestrial targets in 29 spectral bands from .4 to .8 microns.
Dabney, Phillip   +6 more
core   +1 more source

Pareto optimality in multilayer network growth [PDF]

open access: yes, 2018
We model the formation of multi-layer transportation networks as a multi-objective optimization process, where service providers compete for passengers, and the creation of routes is determined by a multi-objective cost function encoding a trade-off ...
A. Cook   +13 more
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Revisão das espécies sul-americanas de Rhopalophora (Coleoptera: Cerambycidae) Revision of the South American species of Rhopalophora (Coleoptera: Cerambycidae)

open access: yesZoologia (Curitiba), 2009
Rhopalophora Audinet-Serville, 1834 is currently composed of 25 species with a distribution ranging from North to South America. Only nine of them were described from South America and have been recorded exclusively from this continent.
Dilma Solange Napp
doaj   +1 more source

Main Results [PDF]

open access: yes, 2007
In this chapter, we present the main results of the 2007 global survey on organic land area, land use and organic farms carried out by SOEL and ...
Sthamer, Dirk   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

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