Results 11 to 20 of about 524,650 (239)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

GRB 221009A: The B.O.A.T. Burst that Shines in Gamma Rays

open access: yesThe Astrophysical Journal Supplement Series
We present a complete analysis of Fermi Large Area Telescope (LAT) data of GRB 221009A, the brightest gamma-ray burst (GRB) ever detected. The burst emission above 30 MeV detected by the LAT preceded, by 1 s, the low-energy (
M. Axelsson   +155 more
doaj   +1 more source

Algae, Macroinvertebrate and Water Quality Relationships at North Campus Open Space

open access: yes, 2023
Algae and macroinvertebrate communities respond to the dissolved oxygen and salinity levels of the water. Dissolved oxygen is required by the macroinvertebrates for respiration. Salinity impacts the algae because every algae has a specific salinity range that they are able to survive in.
Huynh, Lily   +2 more
openaire   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu   +11 more
wiley   +1 more source

ExoClock Project. IV. A Homogeneous Catalog of 620 Updated Exoplanet Ephemerides

open access: yesThe Astrophysical Journal Supplement Series
The ExoClock project is an open platform aiming to monitor exoplanets by integrating observations from space- and ground-based telescopes. This study presents an updated catalog of 620 exoplanet ephemerides, integrating 30,000 measurements from ground ...
A. Kokori   +325 more
doaj   +1 more source

The Right to the City Begins on the Street [PDF]

open access: yes, 2015
streetspublic spacesstreet vendorscity lifecivil rightsprotestStreets are an open and common space being reclaimed by people of all ages, in all kinds of weather, at all times of day and night for purposes never envisioned by planners and designers nor ...

core  

Vector Fall 2016 [PDF]

open access: yes, 2016
Vector is the student engineering magazine on campus. Published by the Student Engineering Council, Vector is completely written, managed, and designed by students for students.
University of Texas at Austin
core   +1 more source

Mucocutaneous Disease Activity and Damage Accrual in Systemic Lupus Erythematosus: Analyses From the Asia‐Pacific Lupus Collaboration Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective This research article aims to describe the prevalence, associations, and health‐related quality of life (HRQoL) impact of mucocutaneous features of systemic lupus erythematosus (SLE). Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analyzed (2013–2021).
Amanda M. Saracino   +42 more
wiley   +1 more source

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