Results 231 to 240 of about 421,739 (314)

Trends in synthetic cathinone detection in seized drug samples submitted to the U.S. DEA's National Forensic Laboratory Information System, 2010-2024. [PDF]

J Anal Toxicol
Fitzgerald ND, Zhu DT, Krotulski AJ, Goldberger BA, Martins SS, Palamar JJ.   +5 more
europepmc   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

Jeannie Robertson: The Other Ballads

Scottish Studies, 1972
Herschel Gower and James Porter
doaj  

Molecular identification of Kudoa thyrsites parasite isolated from Atlantic mackerel (Scomber scombrus) landed in Ireland. [PDF]

Parasitol Res
Királyová V, Brophy D, Giulietti L, Talbot A, Gallagher M, Campbell A, O'Dwyer K.   +6 more
europepmc   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

Advanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai, Jikuang Zhao, Chang Xue, Kailei Xu, Liang Yong, Zhuangwei Zhang, Yi Huang, Jianwei Shuai, Xianzhen Chen, Sheng Nie, Junpeng Xu   +10 more
wiley   +1 more source

Yield Stability and Adaptability of Black Soybean Line BSCM41 Support Bi-Directional Seed Rotation System in Northeast Thailand. [PDF]

Plants (Basel)
Phosuk K, Chinnarat J, Monkham T, Sanitchon J, Khodphuwiang J, Reewarabundit S, Chankeaw S.   +6 more
europepmc   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian, Teizo Yoshimura, Kun Zhao, Chunning Li, Tong Gao, Ziyi Wang, Masayoshi Fujisawa, Toshiaki Ohara, Akihiro Matsukawa   +8 more
wiley   +1 more source

Redescription of the rare, incompletely described <i>Mongolodiaptomus rarus</i> (Ranga Reddy, Sanoamuang & Dumont, 1998) (Copepoda, Calanoida, Diaptomidae), from freshwater habitats in northeast Thailand, with comments on conservation status. [PDF]

PeerJ
Sanoamuang L, Dabseepai P, Koompoot K.
europepmc   +1 more source

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

Advanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian, Jiasha Wu, Fusheng Xu, Yan Zuo, Huaxing Shen, Rui Ji, Luyi Wang, Na Li, Yanting Sun, Yongsheng Yu, Yejiao Shi, Honggang Hu, Feng Xu, Dan Huang, Xiaochun Hu   +14 more
wiley   +1 more source

Epidemiology of glomerular diseases in Northeastern Brazil from 2008-2024. [PDF]

J Bras Nefrol
Sodré AM, Campos MAG, Cutrim ÉMM, Sousa PMB, Oliveira TKM, Teófilo KIM, Guedes FL, Almeida JB, Marques IDB, Alexandre CDS, Vasco RFV, Araújo DV, Ladchumananandasivam FR, Gatto GC, Gomes OV, Costa DMDN, Santana DRM, Muniz MPR, Brito DJA, Salgado Filho N, Neves PDMM, Silva GEB.   +21 more
europepmc   +1 more source