Results 221 to 230 of about 2,152,388 (314)

Oldest well‐preserved euprimate petrosal, from the early Eocene of India (Vastan Lignite Mine, Gujarat)

open access: yesThe Anatomical Record, EarlyView.
Abstract An exquisitely preserved, isolated partial petrosal with associated fragmentary stapes is described from the Vastan Lignite Mine (Gujarat, India), dated to the early Eocene (~54.5 Ma). Several anatomical traits (e.g., large petrosal plate; posterolateral entry of the internal carotid artery to the tympanic cavity; bony tubes surrounding the ...
Mary T. Silcox   +8 more
wiley   +1 more source

First evidence of a mandibular crest in Brasileodactylus Kellner, 1984 (Pterosauria, Pteranodontoidea, Anhangueridae), with comments on pterosaur headcrests

open access: yesThe Anatomical Record, EarlyView.
Abstract Brasileodactylus araripensis Kellner, 1984, is a toothed pterosaur from the Lower Cretaceous Romualdo Formation of the Araripe Basin, Brazil. Traditionally regarded as crestless, the species has been central to debates on anhanguerid taxonomy, as most members of the clade possess well‐developed sagittal cranial or dentary crests.
Anderson da Silva Nascimento   +4 more
wiley   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang   +16 more
wiley   +1 more source

Genetic and Population Analyses Implicate Thyroid‐Related Regulation of RNF144B in Chondrocalcinosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Chondrocalcinosis, characterized by calcium crystal deposition within articular cartilage, affects 5% to 15% of the general population and has recently been identified as an osteoarthritis risk factor. However, its biologic pathways remain unclear.
Yahong Wu   +15 more
wiley   +1 more source

GlycoMAC: A Multiscale Metabolic‐Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a single scale. Here, we present a multiscale mechanistic framework linking molecular, cellular, and macroscopic scales to predict how inputs shape bioprocess ...
Yuming Zeng   +3 more
wiley   +1 more source

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