Results 121 to 130 of about 470,201 (280)
Advanced Science, EarlyView.MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang +12 more
wiley +1 more source
The Role of the “Crimean Factor” in Geopolitical Processes of the Black Sea Region
RUDN Journal of Political ScienceThe role of the “Crimean factor” on geopolitical processes in the Black Sea region is discussed basing on the structural-functional analysis, cross-cultural analysis, and the method of binary oppositions.
Andrey V. Ishin
doaj +1 more source
The most important problems of ancient archeology of the Northern Black Sea region
Исторические исследования (History Studies), 2021 The article is a review of the main problems of ancient archeology of the Northern black sea region and is structured on a chronological basis. First, we consider the problems of the early period of Greek colonization–VII–V centuries BC. the Main research topics are the causes and nature of colonization.
openaire +1 more source
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Advanced Science, EarlyView.Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source
Regional Black Sea Architecture and Consequences for the Regional Cooperation Framework [PDF]
Romanian Journal of European Affairs, 2010 Sometimes considered an asset, other times a liability, the Black Sea started recently to be regarded as a region. However, the Black Sea Region lacks a common vision, often due to the complicated and often inefficient nexus of regional cooperation ...
Alina Homorozean
doaj
Advanced Science, EarlyView.This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang +7 more
wiley +1 more source
The Marmara Sea Gateway since ~16 ky BP: non-catastrophic causes of paleoceanographic events in the Black Sea at 8.4 and 7.15 ky BP [PDF]
, 2007 The Late Quaternary history of connection of the Black Sea to the Eastern Mediterranean has been intensely debated. Ryan, Pitman and coworkers advocate two pulses of outflow from the Black Sea to the world ocean at ~16–14.7 ky BP and ~11–10 ky BP ...
Abrajano, T. +6 more
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Semiconducting THO‐C3N Monolayers for Ultrahigh Anisotropic Carrier Mobility
Advanced Science, EarlyView.A precise site‐specific N‐doping strategy that drives a secondary electronic transition in net W is proposed, enabling the electronic properties transition from metal to Dirac semimetal and ultimately to semiconductor. The obtained THO‐C3N‐2 and THO‐C3N‐3 semiconductors exhibit high carrier mobilities and pronounced mobility anisotropy, with THO‐C3N‐2 ...
Rui Tan +7 more
wiley +1 more source
Accounting for the great divergence [PDF]
, 2013 This paper “accounts” for the Great Divergence between Europe and Asia in two ways. In the sense of measurement: (1) the traditional view, in which the Great Divergence had late medieval origins and was already well under way during the early modern ...
Broadberry, S. N.
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