Results 41 to 50 of about 470,201 (280)

Looking beyond stratification: a model-based analysis of the biological drivers of oxygen deficiency in the North Sea [PDF]

open access: yes, 2016
Low oxygen conditions, often referred to as oxy- gen deficiency, occur regularly in the North Sea, a temperate European shelf sea. Stratification represents a major process regulating the seasonal dynamics of bottom oxygen, yet, low- est oxygen ...
Greenwood, Naomi   +7 more
core   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Ancient economic and social concepts in the Genoese Gasaria Region [PDF]

open access: yes, 2017
The main theme of the article is the consideration of issues related to the presence of the Genoese Republic in the Northern Black Sea region in the 13th - 15th centuries.
Bocharov, Sergey G.
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

A new approach to dating the fallow lands in old-cultivated areas of the steppe zone [PDF]

open access: yes, 2014
We have determined the landing rate of limestone into soil on uneven-aged surfaces (mound and de-posits) in the ancient agricultural steppe region of the Northern Black Sea Region (chora of Kerkinitis) with well represented carbonate soils.
Jakuschenko, D. G.   +2 more
core  

Interaction of the westerlies with the Tibetan Plateau in determining the Mei-Yu termination [PDF]

open access: yes, 2020
This study explores how the termination of the mei-yu is dynamically linked to the westerlies impinging on the Tibetan Plateau. It is found that the mei-yu stage terminates when the maximum upper-tropospheric westerlies shift beyond the northern edge of ...
Chiang, JCH, Kong, W
core  

Cenozoic evolution of the eastern Black Sea: a test of depth-dependent stretching models [PDF]

open access: yes, 2008
Subsidence analysis of the eastern Black Sea basin suggests that the stratigraphy of this deep, extensional basin can be explained by a predominantly pure-shear stretching history.
Edwards, Glyn R.H.   +6 more
core   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou   +12 more
wiley   +1 more source

Skeptouchoi in the Caucasus and the Northern Black Sea region in the ancient era

open access: yesKavkazologiya, 2022
Among the terms used by ancient authors for barbarian rulers is the term skeptouchoi. This article raises the problem of the content of this term to characterize the barbaric societies of the Northern Black Sea region and the Caucasus. Strabo reports on skeptouchoi in the Pre-Caucasus and skeptouchoi in Colchis.
Vdovchenkov Evgeny, Voskresenskiy Andrey
openaire   +2 more sources

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