Results 201 to 210 of about 565,993 (296)

Mapping the Global Clinical Landscape of Pharmacological Therapies for Heart Failure With Preserved Ejection Fraction: An Analysis Based on ClinicalTrials.gov (2003–2025)

iMetaMed, EarlyView.
This study analyzed 236 heart failure with preserved ejection fraction (HFpEF) pharmacological trials registered on ClinicalTrials.gov from 2003 to 2025, revealing a post‐2016 surge (76.3%), U.S. dominance (58.5%), and prominence of SGLT2 inhibitors/novel therapies (each 13.1%).
Yucheng Hou, Jingwei Zhao, Yuqian Tang, Tan Liu, Zhiao Zhang, Ziheng Wang, Han Shen   +6 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Cohort Profile Update: The Northern Ireland Longitudinal Study (NILS). [PDF]

Int J Epidemiol
Lowry E, Shuttleworth I, Wilgar P, McLoughlin C, Connell E.   +4 more
europepmc   +1 more source

Understanding bidirectional and transactional relations in parent and offspring mental health: Using COVID‐19 pandemic data to gain insights

JCPP Advances, EarlyView.
This study found that parent internalising symptoms predicted internalising symptoms in younger children, with no evidence of child‐driven effects. Among adolescents, mental health symptoms showed bidirectional associations with parent internalising symptoms, particularly for externalising symptoms.
Martha Oakes, Lowrie Hilladakis, Polly Waite, Cathy Creswell, Simona Skripkauskaite   +4 more
wiley   +1 more source

High Prevalence of Influenza D Virus Infection in Swine, Northern Ireland. [PDF]

Emerg Infect Dis
Lagan P, Lemon K.
europepmc   +1 more source

Sufficiency of current practice: How well does the Strengths and Difficulties Questionnaire detect clinically elevated posttraumatic stress, anxiety, and depression symptoms in children in care?

JCPP Advances, EarlyView.
Abstract Background It is well‐established that children living in care are at far greater risk of mental health difficulties than their peers. This includes common and trauma‐specific mental health conditions, including depression, anxiety and posttraumatic stress disorder (PTSD).
Eva A. Sprecher, Katherine Shelton, Lisa Holmes, Bethan Carter, Charlotte Robinson, Maryam Javed, Ruby Khan, John MacLeod, Jeongeun Park, Julie Selwyn, Iram Siraj, Ching So, Rachel M. Hiller   +12 more
wiley   +1 more source

Healthy lives, enriched minds: the role of physical health and mental health on educational attainment in Northern Ireland. [PDF]

BMC Public Health
Early E, Miller S, Dunne L, O'Reilly D.
europepmc   +1 more source

Northern Ireland Devolution Monitoring Report: May 2009 [PDF]

, 2009

core  

Factors associated with better emotional, behavioural and educational outcomes in children with mild intellectual difficulties

JCPP Advances, EarlyView.
Abstract Background Children with mild intellectual difficulties (MID) are at increased risk of poor mental health and functional outcomes compared to typically developing children. Previous research has primarily focused on deficit‐based comparisons. However, substantial heterogeneity exists in this population, ranging from significant impairment to ...
Foteini Tseliou, Charlotte A. Dennison, Christopher B. Eaton, Jessica M. Armitage, Frances Rice, Stephan Collishaw   +5 more
wiley   +1 more source