Results 131 to 140 of about 310,438 (262)
The Anatomical Record, EarlyView.Abstract The Late Triassic–Early Jurassic fissures of the Bristol Channel area (southwest England and south Wales) are renowned for their diverse vertebrate faunas. These assemblages have yielded an array of predominantly small‐bodied forms that are crucial to our understanding of the early evolution of several major tetrapod clades.
Ewan H. Bodenham +4 more
wiley +1 more source
Archaeology in Oceania, EarlyView.ABSTRACT This paper reports on the excavation of a cache of stone artefacts, buried on the bank of a waterhole or ‘billabong’ in central western Queensland. This is an extremely rare find, and yet it is the second such site to be reported within less than a 10 km radius.
Yinika L. Perston +5 more
wiley +1 more source
Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies
Animal Research and One Health, EarlyView.Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu +6 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. The variable copy number (CN) of C4 genes and retroviral human endogenous retrovirus K (HERV‐K) element influence its function.
Javier Martínez‐López +156 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE) and is partially driven by type I interferon signaling. Anifrolumab, an approved treatment for patients with SLE, has been investigated in a phase 2 trial in patients with LN receiving standard therapy (TULIP‐LN, ClinicalTrials.gov identifier ...
Andrea Fava +8 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini +19 more
wiley +1 more source
ANK1 and EPB41 Variants and The Risk of Steroid‐Induced Osteonecrosis
Arthritis &Rheumatology, Accepted Article.Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen +21 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objectives Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Lupus patients and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu +2 more
wiley +1 more source
Blended and digital approaches in histology and pathology teaching: A scoping review
Anatomical Sciences Education, EarlyView.Abstract Histology and pathology education is evolving, driven by the integration of digital microscopy with other technological advances. Gaining insight into the impact of this transition, while understanding the perspectives of both students and educators, is important for improving teaching practices. This includes mapping teaching methods, digital
Eleonora Nava +3 more
wiley +1 more source
Essential work, invisible workers: The role of digital curation in COVID‐19 Open Science
Journal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 703-717, April 2025.Abstract In this paper, we examine the role digital curation practices and practitioners played in facilitating open science (OS) initiatives amid the COVID‐19 pandemic. In Summer 2023, we conducted a content analysis of available information regarding 50 OS initiatives that emerged—or substantially shifted their focus—between 2020 and 2022 to address ...
Irene V. Pasquetto +2 more
wiley +1 more source