Results 141 to 150 of about 10,847 (264)

Rock art from at least 67,800 years ago in Sulawesi. [PDF]

open access: yesNature
Oktaviana AA   +39 more
europepmc   +1 more source

Main factors associated with variability in the assessment of the objective response rate. A re‐analysis of the PHEREXA phase 3 clinical trial

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Local investigators (LIs) overestimate the objective response rate (ORR) in comparison to Blinded Independent Central Reviewers (BICR) in oncology. In this study, we re‐analysed data obtained in the PHEREXA trial (NCT01026142) with the following aims: i) to confirm at the single‐patient level the discrepancy observed by analysing ...
Gennaro Daniele   +3 more
wiley   +1 more source

Developing medication independence: The experience of UK teenagers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins   +5 more
wiley   +1 more source

Diversification in the steppe rat snake <i>Elaphe dione</i> (Pallas, 1773) coincides with the Mid-Pleistocene climatic transition of Eurasia. [PDF]

open access: yesPeerJ
Simonov E   +9 more
europepmc   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

Retention of 2011 Fukushima Dai-ichi NPP accident-derived <sup>137</sup>Cs in the northern North Pacific-Bering Sea. [PDF]

open access: yesSci Rep
Inoue M   +6 more
europepmc   +1 more source

Career motivations and perceptions of teaching of 16–19‐year‐olds in England and Wales

open access: yesBritish Educational Research Journal, EarlyView.
Abstract The current study provides an understanding of career‐related motivations of 16–19‐year‐olds in schools and A‐level colleges in England and Wales. The 672 participants (62% women) were asked to complete a modified version of the Motivations for Career Choice and the Persistence Research in Science and Engineering scales and provide comments on
Sophie Thompson‐Lee   +4 more
wiley   +1 more source

Assessing cetacean encounter risk in offshore racing. [PDF]

open access: yesSci Rep
Virgili A   +5 more
europepmc   +1 more source

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