Results 91 to 100 of about 1,428,231 (354)

Rethinking the AI Paradigm for Solubility Prediction of Drug‑Like Compounds with Dual‐Perspective Modeling and Experimental Validation

open access: yesAdvanced Science, EarlyView.
Aqueous solubility governs drug delivery and bioavailability, yet its prediction remains challenging. Utilizing the largest curated dataset of drug‐like molecules, prediction models are constructed through dual‐perspective benchmarking. Stacking methods outperform advanced deep learning due to data constraints. These validated models enabled systematic
Qilin Zhu   +8 more
wiley   +1 more source

[Review of] Richard J. Fapso. Norwegians in Wisconsin [PDF]

open access: yes, 1984
The pamphlet opens with a description of Norway, the land and its agricultural economy, the increased population that resulted from the industrial revolution, and the development of a cash economy.
Meisenheimer, Marilyn
core   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

open access: yesAdvanced Science, EarlyView.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua   +31 more
wiley   +1 more source

Stress‐Induced Melting Controlled Failure Mechanisms of Methane Hydrate

open access: yesAdvanced Science, EarlyView.
We study methane hydrate via nanoindentation and nuclear magnetic resonance (NMR), finding its regional melting and mechanical properties, challenging existing views on hydrogen‐bonded crystals. Abstract Methane hydrate, a kind of nonstoichiometric crystalline, attracted worldwide attentions as a promising substitute energy. Its Dissociation is thought
Yanlong Li   +9 more
wiley   +1 more source

The Need for Pension Reform [PDF]

open access: yes
pension reform ...
Subhash Thakur, Valerie Cerra
core  

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