Results 51 to 60 of about 188,088 (309)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Genetic response to human‐induced habitat changes in the marine environment: A century of evolution of European sprat in Landvikvannet, Norway

open access: yesEcology and Evolution, 2021
Habitat changes represent one of the five most pervasive threats to biodiversity. However, anthropogenic activities also have the capacity to create novel niche spaces to which species respond differently.
María Quintela   +9 more
doaj   +1 more source

Knowledge status and gaps for the North Sea – focusing on discharges. [PDF]

open access: yes, 2008
The Norwegian government will develop a management plan for the Norwegian sector of the North Sea. Mapping of the data requirement related to the interaction between land, coast and ocean and identification of specially vulnerable and valuable areas are ...
Folkestad, Are   +11 more
core  

Historical Arctic Logbooks Provide Insights into Past Diets and Climatic Responses of Cod [PDF]

open access: yes, 2015
Gadus morhua (Atlantic cod) stocks in the Barents Sea are currently at levels not seen since the 1950s. Causes for the population increase last century, and understanding of whether such large numbers will be maintained in the future, are unclear.
Engelhard, Georg H   +4 more
core   +3 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Thyasira ockelmanni (Mollusca: Bivalvia: Veneroidea), A new species of Thyasiridae from the Norwegian Sea

open access: yesFauna Norvegica, 2010
A new species of Thyasiridae, Thyasira ockelmanni n.sp. is described from the abyssal depths of the Norwegian Sea. The generic assignment is tentative and possible alternatives are discussed.
Rozemarijn Keuning, Christoffer Schander
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Lebetus scorpioides and Buenia jeffreysii (Teleostei: Gobiidae) found north of the Arctic Circle

open access: yesFauna Norvegica, 2016
Two gobiid species, Lebetus scorpioides and Buenia jeffreysii, were recorded in northern Norway, for the first time north of the Arctic Circle.
Ingvar Byrkjedal   +2 more
doaj   +1 more source

Chemical composition of the atmospheric aerosols in arctic regions in the summer of 2021

open access: yesЛëд и снег, 2023
Atmospheric aerosol is an important characteristic of the state of the atmospheric air, therefore, in the summer of 2021, atmospheric aerosol samples were collected in the expeditions of the Shirshov Institute of Oceanology of the Russian Academy of ...
L. P. Golobokova   +8 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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