Results 111 to 120 of about 17,630 (176)

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman, Claudio Pedrick, Cara A. Kreck, Ricardo L. Mancera   +3 more
wiley   +1 more source

Unique case of perianal trichostasis spinulosa. [PDF]

JAAD Case Rep
Zhong X, Wei ML.
europepmc   +1 more source

High‐Flow Nasal Oxygen in Early Home Pulmonary Rehabilitation for Exertional Hypoxaemia: A Pilot Randomised Feasibility Trial

Respirology, EarlyView.
Summary This pilot randomised feasibility trial evaluated the feasibility and acceptability of early, intensive home‐based pulmonary rehabilitation (PR) and high‐flow nasal oxygen (HFO) during exercise in patients with exertional hypoxaemia post‐hospitalisation. Early home‐based PR was feasible and safe.
Yingjuan Mok, Jing Wen Foong, Hang Siang Wong, Edwin Chan Shih‐Yen, Norasyikin Hassan, Piyanee Klainin‐Yobas, Li Ching Soh, Amanda Soh, Shi Hua Tan, Xuan Han Koh, Poh Choo Tan, Keith Keat Huat Wong   +11 more
wiley   +1 more source

Comparing the Mechanical and Thermodynamic Definitions of Pressure in Ice Nucleation. [PDF]

J Phys Chem Lett
Montero de Hijes P, Shi K, Vega C, Dellago C.   +3 more
europepmc   +1 more source

Enabling Under Ice Glider Operations: A Backseat Driver Approach

Journal of Field Robotics, EarlyView.
ABSTRACT Polar Oceans are key locations for forcing global ocean circulation, influencing both global climate and biogeochemical cycles. Due to restricted access to these seasonally and perennially ice‐covered regions, these areas are severely undersampled.
Yaomei Wang, Benjamin Allsup, Georgios Salavasidis, Stephen Woodward, Adeniyi Adenaya, Mike Smart, Alexis Johnson, Felipe Marques Dos Santos, Jake Ludgate, Daniel Matterson, Alvaro Lorenzo, J. Alexander Brearley, Alexander Brian Phillips   +12 more
wiley   +1 more source

Protocol for direct in vivo evaluation of the stretch reflex in adult mice. [PDF]

STAR Protoc
Rotterman TM, Casiano-Rivera C, Nardelli P, Nichols TR, Alvarez FJ, Cope TC.   +5 more
europepmc   +1 more source

Hyperspectral species maps and LiDAR‐based structured population models show future forest fire frequency may compromise forest resilience

Remote Sensing in Ecology and Conservation, EarlyView.
Monitoring forest recovery from disturbances at scale requires tracking tree dynamics, yet traditional ground‐based approaches are resource‐intensive. We present a pipeline to parameterize integral projection models (IPMs) using LiDAR data and hyperspectral‐based species maps to assess post‐fire recovery across large, forested areas at the Caribou ...
Jessica McLean, Tommaso Jucker, Alice Rosen, Sean M. McMahon, Roberto Salguero‐Gómez   +4 more
wiley   +1 more source

Evaluating Force Matching as a Parametrization Strategy for the CHARMM36m Force Field Using Phosphorylation. [PDF]

J Phys Chem B
Korn V, Rindfleisch T, Posch S, Underhaug J, Horner A, Miettinen M, Pluhackova K.   +6 more
europepmc   +1 more source

Material‐Dependent Functionalization of CVD‐Grown TMDC Monolayers Probed by Vibrational Nanospectroscopy

Small, EarlyView.
PiFM‐led investigation of material‐specific electrochemical aryl diazonium reduction on 2D transition metal dichalcogenide MoSe2‐WSe2 lateral heterostructure monolayers, with mechanisms explained by molecular dynamics simulations. ABSTRACT Understanding the molecular‐level mechanisms governing covalent functionalization of two‐dimensional ...
Maziar Jafari, Amir Khojastehnezhad, Seyed Faridedin Rafie, Andrey Krayev, Nidal Abu‐Zahra, Mohamed Siaj   +5 more
wiley   +1 more source

Stability analysis and noise reduction of a cone-type poppet valve in an aero-hydraulic system. [PDF]

Sci Rep
Chen W, Chen Y, Xu Y, Zhang L.
europepmc   +1 more source