Results 51 to 60 of about 10,376 (262)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Two novel mutations within FREM1 gene in patients with bifid nose

BMC Pediatrics, 2023
Background Bifid nose is a rare congenital deformity and the etiology is unknown. The purpose of this study was to report genetic variation in family of patients with bifid nose.
Xiaoxue Chen, Baofu Yu, Zi Wang, Qingfeng Li, Chuanchang Dai, Jiao Wei   +5 more
doaj   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Innovative Nasal Splitting Technique for Dual Rhinoplasty and Rhinophyma Management: A Case Report and Literature Review

Archives of Plastic Surgery
Rhinophyma is a deforming disease that affects the nose mainly of Caucasian men. Progressive nasal skin thickening, telangiectasias, and hypertrophy of sebaceous appendages are frequently found in these patients.
Michel L.H.T. Vaena, Bruno Benedetti Pinto, Carlos Weck Roxo   +2 more
doaj   +1 more source

Overcoming the Trade‐Off Between Magnetic Coupling and Electrical Insulation in Soft Magnetic Materials via Nanochain Engineering

Advanced Science, EarlyView.
This study employs a nanochain engineering approach combined with an in situ oxidation strategy to fabricate self‐insulating iron‐based magnetic nanochains, addressing the challenge of balancing magnetic coupling and electrical insulation in soft magnetic materials.
Dingrong Zuo, Lichen Liu, Haibo Ke, Rongsheng Bai, Huaping Ding, Jing Zhou, Zhenxiang Cheng, Peng Yu, Weihua Wang   +8 more
wiley   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source

Annealing‐Induced Plasticity and Strengthening in Metallic Glasses

Advanced Science, EarlyView.
This work challenges the dogma that annealing inevitably embrittles metallic glasses. We demonstrate that sub‐Tg annealing, guided by positive mixing enthalpy and constrained kinetics, can drive a self‐organized compositional fluctuation that creates an interface‐free heterogeneous structure.
Yingjie Zhang, Jinyue Wang, Leqing Liu, Yuan Wu, Yi‐huan Cao, Jiqi Yu, Zhen Tian, Zhichao Lu, Fengshou Li, Qiang Chen, Guosheng Zhang, Laiquan Shen, Yong Yu, Hui Wang, Suihe Jiang, Xiaobin Zhang, Xiongjun Liu, Zhaoping Lu   +17 more
wiley   +1 more source

Artificial Piezoelectric Interface Enables Ultrafast Interfacial Ion Kinetic for Highly‐Sensitive Piezoionic Sensors

Advanced Science, EarlyView.
This study proposes a piezoelectric interface modification strategy to amplify the piezoionic effect. The piezoelectric interface generates an intrinsic electric field, which not only drives rapid ion migration but also concentrates polarized ions on the interface. The flexible sensor delivers superior performance, such as a quick response rate, strong
Yanyu Chen, Xingyue Ling, Rizhong Gao, Xiaohong Zhang, Xi Chen, Chao Lu   +5 more
wiley   +1 more source

Use of Septal Cartilage in Rhinoplasty to Correct Nasal Deformity After Unilateral Cleft Lip and Palate Surgery

Clinical, Cosmetic and Investigational Dentistry, 2022
Hong Loi Nguyen,1 Minh Phuong Hoang,2 Van Minh Nguyen,2 Tan Tai Tran,2 Van Son Le3 1Odonto-Stomatology Center, Hue Central Hospital, Hue City, Vietnam; 2Faculty of Odonto-Stomatology, Hue University of Medicine and Pharmacy, Hue University, Hue City ...
Nguyen HL, Hoang MP, Nguyen VM, Tran TT, Le VS   +4 more
doaj  

Oxygen‐Driven Structural Reorganization by Trace Water Enabling Fast Li‐Ion Transport in a Pliable Solid Electrolyte

Advanced Energy Materials, EarlyView.
Trace water is acting as a constructive mediator in 2LiCl–GaF3, markedly increasing ionic conductivity while reorganizing local coordination. Hydration creates localized Li+ solvation environments and partially dissociates ion pairs, enhancing Li‐ion mobility.
Youngkyung Kim, Jae‐Seung Kim, Kwang Ho Shin, Jingyu Choi, Beom Jin Park, Jinyeong Choe, Jiwon Seo, Chanhyun Park, Jeongjae Lee, Dong‐Hwa Seo, Sung‐Kyun Jung   +10 more
wiley   +1 more source